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Saartje Burgmans

Explore the profile of Saartje Burgmans including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 588
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Recent Articles
1.
van de Haar H, Jansen J, Jeukens C, Burgmans S, van Buchem M, Muller M, et al.
Med Phys . 2017 May; 44(8):4112-4125. PMID: 28493613
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakage. In neurodegenerative disorders such as small vessel disease and dementia, the leakage can be very subtle...
2.
Cleutjens F, Ponds R, Spruit M, Burgmans S, Jacobs H, Gronenschild E, et al.
Front Aging Neurosci . 2017 Apr; 9:88. PMID: 28424613
The neural correlates of cognitive impairment in chronic obstructive pulmonary disease (COPD) are not yet understood. Structural brain abnormalities could possibly be associated with the presence of cognitive impairment through...
3.
van de Haar H, Burgmans S, Jansen J, van Osch M, van Buchem M, Muller M, et al.
Radiology . 2017 Jan; 282(2):615. PMID: 28099097
No abstract available.
4.
Freeze W, Jacobs H, Gronenschild E, Jansen J, Burgmans S, Aalten P, et al.
J Alzheimers Dis . 2016 Sep; 55(1):333-342. PMID: 27662299
Cerebral small vessel disease (cSVD) and amyloid-β (Aβ) deposition often co-exist in (prodromal) dementia, and both types of pathology have been associated with neurodegeneration. We examined whether cSVD and Aβ...
5.
van de Haar H, Jansen J, van Osch M, van Buchem M, Muller M, Wong S, et al.
Neurobiol Aging . 2016 Jul; 45:190-196. PMID: 27459939
The neurovascular unit, which protects neuronal cells and supplies them with essential molecules, plays an important role in the pathophysiology of Alzheimer's Disease (AD). The aim of this study was...
6.
van de Haar H, Burgmans S, Jansen J, van Osch M, van Buchem M, Muller M, et al.
Radiology . 2016 Jun; 281(2):527-535. PMID: 27243267
Purpose To investigate whether the blood-brain barrier (BBB) leaks blood-circulating substances in patients with early forms of Alzheimer disease (AD), and if so, to examine the extent and pattern of...
7.
van de Haar H, Burgmans S, Hofman P, Verhey F, Jansen J, Backes W
Neurosci Biobehav Rev . 2014 Dec; 49:71-81. PMID: 25524876
Increasing evidence indicates that blood-brain barrier (BBB) impairment may play a role in the pathophysiology of cognitive decline and dementia. In vivo imaging studies are needed to quantify and localize...
8.
Burgmans S, van de Haar H, Verhey F, Backes W
J Alzheimers Dis . 2013 Apr; 35(4):859-73. PMID: 23542866
To date, the exact pathogenesis of dementia is still unknown. The most frequently hypothesized initiating factor is an accumulation of the protein amyloid-β in the brain, which has been associated...
9.
Echavarri C, Burgmans S, Uylings H, Cuesta M, Peralta V, Kamphorst W, et al.
J Alzheimers Dis . 2012 Sep; 33(3):715-21. PMID: 23001706
Neuropsychiatric symptoms (NPSs) have a large impact on the quality of life of patients with dementia. A few studies have compared neuropsychiatric disturbances between dementia subtypes, but the results were...
10.
Jacobs H, van Boxtel M, Gronenschild E, Williams V, Burgmans S, Uylings H, et al.
Curr Alzheimer Res . 2012 Aug; 9(9):1097-105. PMID: 22920268
Structural brain changes precede cognitive and clinical symptoms in Alzheimer's disease (AD). We aimed to examine the gray and white matter tissue changes in individuals with memory decline over a...