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S Zachary Swartz

Explore the profile of S Zachary Swartz including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 325
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Recent Articles
1.
Clarke D, Kane A, Perillo M, Lowe C, Swartz S
Development . 2024 Aug; 151(20). PMID: 39171380
Delivering molecular tools into oocytes is essential for developmental and reproductive biology. Microinjection, the conventional method, is equipment intensive, often technically challenging and has a low yield, and is impractical...
2.
Perillo M, Swartz S, Pieplow C, Wessel G
Nat Commun . 2023 May; 14(1):2402. PMID: 37160908
A fundamental goal in the organogenesis field is to understand how cells organize into tubular shapes. Toward this aim, we have established the hydro-vascular organ in the sea star Patiria...
3.
Pal D, Visconti F, Sepulveda-Ramirez S, Swartz S, Shuster C
Methods Mol Biol . 2022 Jan; 2415:1-17. PMID: 34972942
The early embryos of sea urchins and other echinoderms have served as experimental models for the study of cell division since the nineteenth century. Their rapid development, optical clarity, and...
4.
Perillo M, Swartz S, Wessel G
Dev Biol . 2021 Dec; 482:28-33. PMID: 34863708
Primordial germ cells (PGCs) are specified by diverse mechanisms in early development. In some animals, PGCs are specified via inheritance of maternal determinants, while in others, in a process thought...
5.
Swartz S, Tan T, Perillo M, Fakhri N, Wessel G, Wikramanayake A, et al.
Curr Biol . 2021 Nov; 31(24):5633-5641.e4. PMID: 34739818
The organismal body axes that are formed during embryogenesis are intimately linked to intrinsic asymmetries established at the cellular scale in oocytes. However, the mechanisms that generate cellular asymmetries within...
6.
Swartz S, Nguyen H, McEwan B, Adamo M, Cheeseman I, Kettenbach A
Elife . 2021 Aug; 10. PMID: 34342579
Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing functions. To define the mechanisms that enable the oocyte-to-embryo transition, we performed...
7.
Swartz S, McKay L, Su K, Bury L, Padeganeh A, Maddox P, et al.
Dev Cell . 2019 Aug; 51(1):35-48.e7. PMID: 31422918
Centromeres provide a robust model for epigenetic inheritance as they are specified by sequence-independent mechanisms involving the histone H3-variant centromere protein A (CENP-A). Prevailing models indicate that the high intrinsic...
8.
Oulhen N, Swartz S, Wang L, Wikramanayake A, Wessel G
Dev Biol . 2019 May; 452(1):34-42. PMID: 31075220
Specification of the primordial germ cells (PGCs) is essential for sexually reproducing animals. Although the mechanisms of PGC specification are diverse between organisms, the RNA binding protein Nanos is consistently...
9.
Oulhen N, Swartz S, Laird J, Mascaro A, Wessel G
Development . 2017 Feb; 144(7):1201-1210. PMID: 28235822
Stem cells in animals often exhibit a slow cell cycle and/or low transcriptional activity referred to as quiescence. Here, we report that the translational activity in the primordial germ cells...
10.
Swartz S
Mol Reprod Dev . 2016 May; 83(5):375. PMID: 27232269
No abstract available.