S W Michnick
Overview
Explore the profile of S W Michnick including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
767
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Recent Articles
1.
Stefan E, Aquin S, Berger N, Landry C, Nyfeler B, Bouvier M, et al.
Proc Natl Acad Sci U S A
. 2007 Oct;
104(43):16916-21.
PMID: 17942691
The G protein-coupled receptor (GPCR) superfamily represents the most important class of pharmaceutical targets. Therefore, the characterization of receptor cascades and their ligands is a prerequisite to discovering novel drugs....
2.
Campbell-Valois F, Michnick S
J Mol Biol
. 2006 Dec;
365(5):1559-77.
PMID: 17137592
The ras binding domain (RBD) of the Ser/Thr kinase c-Raf/Raf-1 spans 78 residues and adopts a structure characteristic of the beta-grasp ubiquitin-like topology. Recently, the primary sequence of Raf RBD...
3.
Campbell-Valois F, Tarassov K, Michnick S
J Mol Biol
. 2006 Aug;
362(1):151-71.
PMID: 16916524
The contributions of specific residues to the delicate balance between function, stability and folding rates could be determined, in part by [corrected] comparing the sequences of structures having identical folds,...
4.
Campbell-Valois F, Tarassov K, Michnick S
Proc Natl Acad Sci U S A
. 2005 Oct;
102(42):14988-93.
PMID: 16214894
Most protein topologies rarely occur in nature, thus limiting our ability to extract sequence information that could be used to predict structure, function, and evolutionary constraints on protein folds. In...
5.
Michnick S
Proc Natl Acad Sci U S A
. 2002 Dec;
99(26):16513-5.
PMID: 12486243
No abstract available.
6.
Remy I, Galarneau A, Michnick S
Methods Mol Biol
. 2002 Jan;
185:447-59.
PMID: 11769008
No abstract available.
7.
Michnick S
Curr Opin Struct Biol
. 2001 Aug;
11(4):472-7.
PMID: 11495741
The study of protein--protein interactions is central to understanding the chemical machinery that makes up the living cell. Until recently, facile methods to study these processes in intact, living cells...
8.
Subramaniam R, Desveaux D, Spickler C, Michnick S, Brisson N
Nat Biotechnol
. 2001 Aug;
19(8):769-72.
PMID: 11479572
The protein NPR1/NIM1 is required for the induction of systemic acquired resistance (SAR) in plants and has been shown to interact with members of the TGA/OBF family of basic leucine...
9.
Remy I, Michnick S
Proc Natl Acad Sci U S A
. 2001 Jul;
98(14):7678-83.
PMID: 11438723
Functional annotation of novel genes can be achieved by detection of interactions of their encoded proteins with known proteins followed by assays to validate that the gene participates in a...
10.
Michnick S
Chem Biol
. 2001 Jan;
7(12):R217-21.
PMID: 11137822
The cellular chemical machinery controlling all living processes is mediated by macroassemblies of enzymes and nucleic acids. These complexes form, break up in different orders and reorganize in ways that...