S W Burchiel
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Explore the profile of S W Burchiel including associated specialties, affiliations and a list of published articles.
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58
Citations
416
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Recent Articles
11.
Davila D, Lane J, Lauer F, Burchiel S
J Toxicol Environ Health A
. 2000 Mar;
56(4):249-61.
PMID: 10706243
It has been well established that certain polycyclic aromatic hydrocarbons (PAHs), such as 7,12-dimethylbenz[a]anthracene (DMBA), 3-methylcholanthrene (3MC), and benzo[a]pyrene (BaP), produce immunotoxicity and cancer in rodents and that these effects...
12.
Burchiel S, Lauer F, Gurule D, Mounho B, Salas V
Methods
. 1999 Oct;
19(1):28-35.
PMID: 10525435
Flow cytometry is an emerging technology that has numerous applications to immunotoxicity testing. The use and development of high-speed single-cell laser-based assays capable of quantitation of fluorescence, light scatter, and...
13.
Tannheimer S, Lauer F, Lane J, Burchiel S
Mol Carcinog
. 1999 May;
25(1):48-54.
PMID: 10331744
Carcinogenic polycyclic aromatic hydrocarbons and a halogenated aromatic hydrocarbon, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), were evaluated for their effects on intracellular Ca2+ in the human mammary epithelial cell line MCF-10A. After two 18-h...
14.
15.
Salas V, Burchiel S
Toxicol Appl Pharmacol
. 1998 Aug;
151(2):367-76.
PMID: 9707513
Numerous studies have demonstrated an association between polycyclic aromatic hydrocarbons (PAHs) and lymphocyte toxicity. The present study shows that, consistent with its effects on Ca2+ homeostasis, benzo[a]pyrene (BaP) induces apoptosis...
16.
Tannheimer S, Ethier S, Caldwell K, Burchiel S
Carcinogenesis
. 1998 Jul;
19(7):1291-7.
PMID: 9683191
Previous studies in this laboratory have shown that polycyclic aromatic hydrocarbons, such as benzo[a]pyrene (BaP), and certain halogenated aromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), modulate receptor signaling pathways in human...
17.
Mounho B, Burchiel S
Toxicol Appl Pharmacol
. 1998 Mar;
149(1):80-9.
PMID: 9512730
Previous studies performed in this laboratory have shown that certain benzo(a)pyrene (BaP) metabolites, such as benzo(a)pyrene-7,8-dihydrodiol (BaP-7,8-diol) and benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE), were more effective in elevating intracellular Ca2+ in normal human...
18.
Mounho B, Davila D, Burchiel S
Toxicol Appl Pharmacol
. 1997 Aug;
145(2):323-30.
PMID: 9266805
Previous studies have demonstrated that polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP) and 7,12-dimethybenz[a]anthracene (DMBA), and possibly 2,3,7,8-tetrachlorodibenzo(p)dioxin (TCDD), may exert their immunosuppressive effects by altering intracellular Ca2+ homeostasis...
19.
Burchiel S, Kerkvliet N, Gerberick G, Lawrence D, Ladics G
Fundam Appl Toxicol
. 1997 Jul;
38(1):38-54.
PMID: 9268604
Flow cytometry is a unique technology useful in the examination of effects of immunotoxic agents on target cells of the immune system. The purpose of this workshop was to provide...
20.
Tannheimer S, Barton S, Ethier S, Burchiel S
Carcinogenesis
. 1997 Jun;
18(6):1177-82.
PMID: 9214600
Previous studies have shown that polycyclic aromatic hydrocarbons (PAHs) mobilize intracellular Ca2+ in human T cells by inositol trisphosphate-dependent mechanisms resulting from activation of phospholipase C-gamma by SRC-related protein tyrosine...