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S T Suhr

Explore the profile of S T Suhr including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 592
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Recent Articles
1.
Suhr S, Senut M, Whitelegge J, Faull K, Cuizon D, Gage F
J Cell Biol . 2001 Apr; 153(2):283-94. PMID: 11309410
Proteins with expanded polyglutamine (polyQ) tracts have been linked to neurodegenerative diseases. One common characteristic of expanded-polyQ expression is the formation of intracellular aggregates (IAs). IAs purified from polyQ-expressing cells...
2.
Taupin P, Ray J, Fischer W, Suhr S, Hakansson K, Grubb A, et al.
Neuron . 2001 Jan; 28(2):385-97. PMID: 11144350
We have purified and characterized a factor, from the conditioned medium of neural stem cell cultures, which is required for fibroblast growth factor 2's (FGF-2) mitogenic activity on neural stem...
3.
Senut M, Suhr S, Kaspar B, Gage F
J Neurosci . 2000 Jan; 20(1):219-29. PMID: 10627599
Expanded polyglutamine (polyQ) tracts have been linked to a new class of human disease characterized by psychiatric/motor syndromes associated with specific patterns of neurodegeneration. We have used a direct viral...
4.
Suhr S, Gage F
Arch Neurol . 1999 Apr; 56(3):287-92. PMID: 10190818
Only a handful of the hundreds of known vertebrate retroviruses have been deliberately subverted for use as carriers of recombinant genetic material. Retroviruses receive their name from the fact that...
5.
Suhr S, Gil E, Senut M, Gage F
Proc Natl Acad Sci U S A . 1998 Jul; 95(14):7999-8004. PMID: 9653129
Our studies of the Bombyx mori ecdysone receptor (BE) revealed that, unlike the Drosophila melanogaster ecdysone receptor (DE), treatment of BE with the ecdysone agonist tebufenozide stimulated high level transactivation...
6.
Senut M, Suhr S, Gage F
J Clin Invest . 1998 May; 101(8):1565-71. PMID: 9541485
The delivery of biologically active factors to the developing mammalian embryo by in utero gene transfer has generated considerable interest but limited success. The chorioallantoic placenta is a potential alternative...
7.
Fagan A, Suhr S, Peterson D, Holtzman D, Gage F
J Neurosci . 1997 Apr; 17(7):2499-511. PMID: 9065510
To investigate the molecular mechanisms of cholinergic sprouting in the hippocampus after removal of entorhinal cortical inputs, we evaluated trophic factor gene expression in the denervated hippocampus. Despite the proposed...
8.
Senut M, Suhr S, Gage F
Nat Biotechnol . 1996 Dec; 14(13):1650-1. PMID: 9634841
No abstract available.
9.
Gage F, Coates P, Palmer T, Kuhn H, Fisher L, Suhonen J, et al.
Proc Natl Acad Sci U S A . 1995 Dec; 92(25):11879-83. PMID: 8524867
The dentate gyrus of the hippocampus is one of the few areas of the adult brain that undergoes neurogenesis. In the present study, cells capable of proliferation and neurogenesis were...
10.
Senut M, Tuszynski M, Raymon H, Suhr S, Liou N, Jones K, et al.
Exp Neurol . 1995 Sep; 135(1):36-55. PMID: 7556552
Neurotrophin 3 (NT3) belongs to the neurotrophin family, which also includes nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 4/5. NT3 mRNA is widely expressed in the rodent nervous system,...