S R James
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Explore the profile of S R James including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
1508
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Recent Articles
1.
Walter Anthony K, Anthony P, Hasson N, Edgar C, Sivan O, Eliani-Russak E, et al.
Nat Commun
. 2024 Jul;
15(1):6056.
PMID: 39025864
Landscape drying associated with permafrost thaw is expected to enhance microbial methane oxidation in arctic soils. Here we show that ice-rich, Yedoma permafrost deposits, comprising a disproportionately large fraction of...
2.
Ptasinska A, Assi S, Mannari D, James S, Williamson D, Dunne J, et al.
Leukemia
. 2012 Feb;
26(8):1829-41.
PMID: 22343733
The t(8;21) translocation fuses the DNA-binding domain of the hematopoietic master regulator RUNX1 to the ETO protein. The resultant RUNX1/ETO fusion protein is a leukemia-initiating transcription factor that interferes with...
3.
James S, Franklyn J, Reaves B, Smith V, Chan S, Barrett T, et al.
Endocrinology
. 2008 Nov;
150(4):1961-9.
PMID: 19022891
Thyroid hormones are essential for the normal growth and development of the fetus, and even small alterations in maternal thyroid hormone status during early pregnancy may be associated with neurodevelopmental...
4.
Richa E, Stowers R, Tauscher C, Benidt G, Van Valkenburg J, Bryant S, et al.
Vox Sang
. 2007 Jun;
93(1):92.
PMID: 17547573
No abstract available.
5.
James S, Link P, Karpf A
Oncogene
. 2006 May;
25(52):6975-85.
PMID: 16715135
We examined the function of two key DNA methyltransferase (DNMT) enzymes in epigenetic regulation of X-linked cancer/germline (CG-X) antigen genes in human cancer cells, using MAGE-A1, NY-ESO-1, and XAGE-1 as...
6.
Lothgren A, McCartney M, Rupp Thuresson E, James S
Biochim Biophys Acta
. 2001 May;
1545(1-2):20-9.
PMID: 11342028
Signalling through the leptin receptor has been shown to activate the SH2 domain-containing tyrosine phosphatase SHP-2 through tyrosine phosphorylation. The human leptin receptor contains five tyrosine residues in the cytoplasmic...
7.
Ellis M, James S, Perisic O, Downes C, Williams R, Katan M
J Biol Chem
. 1998 Jun;
273(19):11650-9.
PMID: 9565585
Structural studies of phospholipase C delta1 (PLCdelta1) in complexes with the inositol-lipid headgroup and calcium identified residues within the catalytic domain that could be involved in substrate recognition, calcium binding,...
8.
Hickinson D, Lucocq J, Towler M, Clough S, James J, James S, et al.
Curr Biol
. 1998 Feb;
7(12):987-90.
PMID: 9382841
The eukaryotic trans-Golgi network (TGN) is a key site for the formation of transport vesicles destined for different intracellular compartments [1]. A key marker for the mammalian TGN is TGN38/46...
9.
James S, Downes C
Cell Signal
. 1997 Aug;
9(5):329-36.
PMID: 9376212
The production of the intracellular second messengers inositol (1,4,5)-trisphosphate (InsP3) and sn 1,2-diacylglycerol (DG) in response to a wide variety of extracellular primary messengers is achieved by an extended family...
10.
Alessi D, James S, Downes C, Holmes A, Gaffney P, Reese C, et al.
Curr Biol
. 1997 Apr;
7(4):261-9.
PMID: 9094314
Background: Protein kinase B (PKB), also known as c-Akt, is activated rapidly when mammalian cells are stimulated with insulin and growth factors, and much of the current interest in this...