S P Fling
Overview
Explore the profile of S P Fling including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
465
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Recent Articles
1.
Louie K, Weiner L, Du J, Kochounian H, Fling S, Wei W, et al.
Gene Ther
. 2005 Mar;
12(14):1145-53.
PMID: 15772685
With the ultimate goal of developing a novel treatment for multiple sclerosis (MS), we have developed a cell-based gene therapy protocol for the treatment of murine experimental autoimmune encephalomyelitis (EAE),...
2.
Coler R, Campos-Neto A, Ovendale P, DAY F, Fling S, Zhu L, et al.
J Immunol
. 2001 May;
166(10):6227-35.
PMID: 11342645
The development of an effective vaccine against Mycobacterium tuberculosis is a research area of intense interest. Mounting evidence suggests that protective immunity to M. tuberculosis relies on both MHC class...
3.
Fling S, Sutherland R, Steele L, Hess B, DOrazio S, Maisonneuve J, et al.
Proc Natl Acad Sci U S A
. 2001 Feb;
98(3):1160-5.
PMID: 11158611
During infection with Chlamydia trachomatis, CD8(+) T cells are primed, even though the bacteria remain confined to a host cell vacuole throughout their developmental cycle. Because CD8(+) T cells recognize...
4.
Lewinsohn D, Zhu L, Madison V, Dillon D, Fling S, Reed S, et al.
J Immunol
. 2000 Dec;
166(1):439-46.
PMID: 11123322
Previous studies in murine and human models have suggested an important role for HLA Ia-restricted CD8(+) T cells in host defense to Mycobacterium tuberculosis (Mtb). Therefore, understanding the Ags presented...
5.
Fling S, Rak J, Muczynski K, Arp B, Pious D
J Exp Med
. 1997 Nov;
186(9):1469-80.
PMID: 9348304
We and others have shown that the products of the HLA-DM locus are required for the intracellular assembly of major histocompatibility complex class II molecules with cognate peptides for antigen...
6.
Prasad S, Fling S, Gregerson D
J Autoimmun
. 1997 Feb;
10(1):1-9.
PMID: 9080294
Autoreactive T cell hybridomas specific for pathogenic peptides of retinal S-Ag require a novel radiosensitive APC activity for IL-2 secretion that is distinct from Ag presentation by MHC class II....
7.
Prasad S, Fling S, Gregerson D
Int Immunol
. 1995 Nov;
7(11):1787-98.
PMID: 8580077
T cell hybridomas were generated from a LEW rat T cell line specific for the uveitogenic peptide bov-B1 of bovine retinal S-antigen. Using these autoreactive hybridomas, IL-2 production and activation-induced...
8.
Fling S, Arp B, Pious D
Nature
. 1994 Apr;
368(6471):554-8.
PMID: 8139690
Major histocompatibility complex (MHC) class II molecules are highly polymorphic cell-surface glycoproteins that present antigenic peptides to CD4+ T lymphocytes. The normal assembly of class II molecules with cognate peptides...
9.
Fling S, Gold D, Gregerson D
Cell Immunol
. 1992 Jul;
142(2):275-86.
PMID: 1320462
The restricted usage of particular T cell receptor beta chain genes in autoimmune disease was studied in LEW rats using T cell hybridomas specific for an immunodominant sequence of bovine...
10.
Gregerson D, Fling S, Donoso L, Gold D
Curr Eye Res
. 1992 Jan;
11 Suppl:67-74.
PMID: 1385044
Several observations in the characterization of EAU are examined. First, sequences of heterologous S-Ag (bovine S-Ag in LEW rats) which induce strong in vitro T cell proliferative responses are dissociated...