S P Cairns
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Explore the profile of S P Cairns including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
277
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Recent Articles
1.
Ijpma G, Al-Jumaily A, Cairns S, Sieck G
Am J Physiol Lung Cell Mol Physiol
. 2010 Sep;
299(6):L898-904.
PMID: 20817779
We present a systematic quantitative analysis of power-law force relaxation and investigate logarithmic superposition of force response in relaxed porcine airway smooth muscle (ASM) strips in vitro. The term logarithmic...
2.
Cairns S, Lindinger M
J Physiol
. 2008 Jul;
586(17):4039-54.
PMID: 18591187
During intense exercise or electrical stimulation of skeletal muscle the concentrations of several ions change simultaneously in interstitial, transverse tubular and intracellular compartments. Consequently the functional effects of multiple ionic...
3.
Cairns S, Robinson D, Loiselle D
Exp Physiol
. 2008 Mar;
93(7):851-62.
PMID: 18344260
We present a curve-fitting approach that permits quantitative comparisons of fatigue profiles obtained with different stimulation protocols in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles of mice....
4.
Cairns S, Hing W, Slack J, Mills R, Loiselle D
J Appl Physiol (1985)
. 1998 May;
84(4):1395-406.
PMID: 9516209
The possible role of altered extracellular Ca2+ concentration ([Ca2+]o) in skeletal muscle fatigue was tested on isolated slow-twitch soleus and fast-twitch extensor digitorum longus muscles of the mouse. The following...
5.
Cairns S, Hing W, Slack J, Mills R, Loiselle D
Am J Physiol
. 1997 Aug;
273(2 Pt 1):C598-611.
PMID: 9277357
Increasing extracellular K+ concentration ([K+]o) from 4 to 7-14 mM reduced both tetanic force and resting membrane potential (Em) in isolated slow-twitch soleus and fast-twitch extensor digitorum longus (EDL) muscles...
6.
Cairns S, Flatman J, Clausen T
Pflugers Arch
. 1995 Oct;
430(6):909-15.
PMID: 8594543
An increased extracellular K+ concentration ([K+]0) is thought to cause muscle fatigue. We studied the effects of increasing [K+]0 from 4mM to 8-14mM on tetanic contractions in isolated bundles of...
7.
Cairns S, Dulhunty A
Muscle Nerve
. 1995 Aug;
18(8):890-8.
PMID: 7630351
High-frequency fatigue (HFF), the decline of force during continuous tetanic stimulation (lasting 4-40 s), was studied in isolated bundles of rat skeletal muscle fibers. HFF was slower in slow-twitch soleus...
8.
Cairns S, Dulhunty A
Am J Physiol
. 1994 May;
266(5 Pt 1):C1204-9.
PMID: 8203484
The effect of terbutaline (a beta 2-adrenergic agonist) on high-frequency fatigue (HFF) was studied in small bundles of rat soleus muscle fibers. HFF, the decline in force during continuous stimulation...
9.
Cairns S, Dulhunty A
Muscle Nerve
. 1993 Dec;
16(12):1317-25.
PMID: 8232387
We examined the mechanism(s) which allow terbutaline, a beta 2-adrenergic agonist, to increase isometric force in bundles of normal and denervated rat soleus fibers. Terbutaline (10 mumol/L) potentiated tetanic contractions...
10.
Cairns S, Dulhunty A
Br J Pharmacol
. 1993 Nov;
110(3):1133-41.
PMID: 8298802
1. The aim of the experiments was to examined the effects of beta-adrenoceptor activation on twitch and tetanic contractions in fast- and slow-twitch mammalian skeletal muscle fibres. Isometric force was...