S O Sharrow
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Explore the profile of S O Sharrow including associated specialties, affiliations and a list of published articles.
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141
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2958
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Recent Articles
11.
Mackall C, Bare C, Granger L, Sharrow S, Titus J, Gress R
J Immunol
. 1996 Jun;
156(12):4609-16.
PMID: 8648103
Thymic regenerative capacity in humans decreases with age, suggesting that thymic-independent pathways of T cell regeneration may predominate during adulthood. Using a murine bone marrow transplantation model, we present evidence...
12.
Roberts J, Sharrow S, Singer A
Cell Immunol
. 1995 Mar;
161(1):22-7.
PMID: 7867081
Cell surface TCR expression by developing thymocytes is actively regulated during ontogeny. Whereas most immature CD4+CD8+ thymocytes express low levels of TCR alpha beta, mature CD4+ and CD8+ thymocytes express...
13.
DeLuca D, Bluestone J, Shultz L, Sharrow S, Tatsumi Y
J Immunol Methods
. 1995 Jan;
178(1):13-29.
PMID: 7829862
Fetal thymus organ culture (FTOC) has become widely used to investigate the impact of immunomodulators on T cell development. However, these studies have given variable results among different laboratories. In...
14.
Kearse K, Takahama Y, Punt J, Sharrow S, Singer A
J Exp Med
. 1995 Jan;
181(1):193-202.
PMID: 7528767
Differentiation of immature CD4+ CD8+ thymocytes into mature CD4+ or CD8+ T cells occurs within the thymus and is dependent upon expression of antigen receptor complexes (T cell receptor [TCR])...
15.
Benveniste P, Takahama Y, Wiest D, Nakayama T, Sharrow S, Singer A
Proc Natl Acad Sci U S A
. 1994 Jul;
91(15):6933-7.
PMID: 8041724
Immature precursor cells are induced in the thymus to express clonotypic T-cell antigen receptors (TCRs) and to differentiate into mature T cells. Perhaps the least understood event which occurs during...
16.
Sharrow S, Barden L, Singer A, Katz S
J Immunol
. 1994 Jul;
153(1):110-6.
PMID: 8207229
Epidermal Langerhans cells are derived from cells of bone marrow origin and, as the primary APC population in the skin, are responsible for initiation of many immune responses. Consequently, cell...
17.
Lee M, Sharrow S, Farr A, Singer A, Udey M
J Immunol
. 1994 Jun;
152(12):5653-9.
PMID: 8207198
Cadherins mediate homotypic adhesion between lineage-related cells in epithelia and other tissues. One cadherin, E-cadherin, is also responsible for adhesion of murine epidermal Langerhans cells to keratinocytes in vitro, and...
18.
Punt J, Osborne B, Takahama Y, Sharrow S, Singer A
J Exp Med
. 1994 Feb;
179(2):709-13.
PMID: 8294878
CD4+CD8+ thymocytes expressing self-reactive T cell antigen receptors (TCR) are deleted in the thymus as a consequence of TCR/self-antigen/major histocompatibility complex interactions. However, the signals that are necessary to initiate...
19.
Lee M, Tang A, Sharrow S, Udey M
Epithelial Cell Biol
. 1994 Jan;
3(4):149-55.
PMID: 7550606
Cadherins mediate homotypic intercellular adhesion in epidermis and other epithelia. E-cadherin is also involved in interactions between murine epidermal Langerhans cells (LC) and keratinocytes (KC). Dendritic epidermal T cells (DETC)...
20.
Vacchio M, Granger L, Kanagawa O, Malissen B, Tomonari K, Sharrow S, et al.
J Immunol
. 1993 Aug;
151(3):1322-7.
PMID: 8101542
This study has evaluated whether preferential pairing occurs between TCR alpha- and beta-chains expressing specific V alpha and V beta gene products in the mature peripheral T cell population, as...