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S O Brennan

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Articles 130
Citations 865
Followers 0
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Recent Articles
1.
Marchi R, Linares M, Rojas H, Ruiz-Saez A, Meyer M, Casini A, et al.
BMC Hematol . 2018 Jan; 17:22. PMID: 29299315
Background: Abnormal fibrinogens can be caused by clinically silent hereditary mutations. A new case was detected accidentally in an 11-year-old girl when routine pre-operative coagulation tests were performed for nasal...
2.
Brennan S, Oliver J, Davis R
J Thromb Haemost . 2011 May; 9(7):1410-2. PMID: 21605328
No abstract available.
3.
Brennan S, Davis R, Chitlur M
Thromb Haemost . 2010 Feb; 103(2):478-9. PMID: 20126833
No abstract available.
4.
Dear A, Brennan S, Sheat M, Faed J, George P
Haematologica . 2007 Nov; 92(11):e111-7. PMID: 18024387
Disorders of fibrinogen are usually caused by genetic mutations that result in low protein levels (hypofibrinogenemia) or an abnormal molecule (dysfibrinogenemia). However, environmental and plasma factors can have an acquired...
5.
Dear A, Daly J, Brennan S, Tuckfield A, George P
J Thromb Haemost . 2006 Jan; 4(2):471-2. PMID: 16420582
No abstract available.
6.
Dear A, Dempfle C, Brennan S, Kirschstein W, George P
J Thromb Haemost . 2004 Dec; 2(12):2194-9. PMID: 15613026
Background: In recent years it has become clear that the molecular investigation of hypofibrinogenemia provides unique insight into regions of the fibrinogen molecule that are important in molecular assembly, secretion...
7.
Mushunje A, Evans G, Brennan S, Carrell R, Zhou A
J Thromb Haemost . 2004 Dec; 2(12):2170-7. PMID: 15613023
It is now apparent that the inactivated latent and cleaved conformers of antithrombin (AT) are of pathological significance. Using a single-run electrophoretic technique that allows the quantitative assessment of these...
8.
Maghzal G, Brennan S, Homer V, George P
Cell Mol Life Sci . 2004 Jun; 61(12):1427-38. PMID: 15197468
Congenital hypofibrinogenaemia is characterized by abnormally low levels of fibrinogen and is usually caused by heterozygous mutations in the fibrinogen chain genes (alpha, beta and gamma). However, it does not...
9.
Homer V, Mullin J, Brennan S, Barr A, George P
J Thromb Haemost . 2003 Jul; 1(6):1245-50. PMID: 12871326
A young woman with a history of menorrhagia and easy bruising presented with a functional fibrinogen concentration of 1.8 mg mL(-1), a gravimetric concentration of 3.3 mg mL(-1) and a...
10.
Florkowski C, Walmsley T, Brennan S, George P
Postgrad Med J . 2003 Apr; 79(929):174-5. PMID: 12697922
A woman was screened for diabetes using glycated haemoglobin (HbA1c). Vastly different results were obtained by high performance liquid chromatography (45%), immunoassay (2.9%), and affinity chromatography (4.2%) compared with the...