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S M Manzella

Explore the profile of S M Manzella including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 137
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Recent Articles
1.
Wirkowski E, Gottesman M, MAZER C, Brody G, Manzella S
J Stroke Cerebrovasc Dis . 2007 Sep; 8(5):291-4. PMID: 17895177
Thrombolysis for acute ischemic stroke has become a reality. The aim of our study was to assess the opportunity and practicality of establishing acute stroke treatment in a hospital that...
2.
Manzella S
Clin Excell Nurse Pract . 2001 Mar; 4(4):205-11. PMID: 11261080
Complementary, or alternative, healthcare practices are being incorporated into approximately 4 out of 10 Americans' daily health practices. The out-of-pocket expense for such healthcare use was estimated at $21.2 billion...
3.
Manzella S, Galante K
J Neurosci Nurs . 2001 Jan; 32(6):306-10. PMID: 11155344
Stroke remains one of the major causes of death and permanent disability in the United States, ranking as the third leading cause of death behind heart disease and cancer. It...
4.
Keusch J, Manzella S, Nyame K, Cummings R, Baenziger J
J Biol Chem . 2000 Jun; 275(33):25315-21. PMID: 10854428
We have cloned Gb(3) synthase, the key alpha1, 4-galactosyltransferase in globo-series glycosphingolipid (GSL) synthesis, via a phenotypic screen, which previously yielded iGb(3) synthase, the alpha1,3-galactosyltransferase required in isoglobo-series GSL (Keusch,...
5.
Keusch J, Manzella S, Nyame K, Cummings R, Baenziger J
J Biol Chem . 2000 Jun; 275(33):25308-14. PMID: 10854427
The large array of different glycolipids described in mammalian tissues is a reflection, in part, of diverse glycosyltransferase expression. Herein, we describe the cloning of a UDP-galactose: beta-d-galactosyl-1,4-glucosylceramide alpha-1, 3-galactosyltransferase...
6.
Manzella S, Dharmesh S, Cohick C, Soares M, Baenziger J
J Biol Chem . 1997 Feb; 272(8):4775-82. PMID: 9030532
Successful pregnancy is dependent upon an array of signaling proteins secreted by the trophoblast cells of the placenta. Among these is a group of proteins related to pituitary prolactin, known...
7.
Hooper L, Manzella S, Baenziger J
FASEB J . 1996 Aug; 10(10):1137-46. PMID: 8751716
Carbohydrates attached to proteins and lipids characteristically display complex and heterogeneous structures. However, it is becoming increasingly clear that carbohydrates with definite biological functions also exhibit unique structural features. A...
8.
Manzella S, Hooper L, Baenziger J
J Biol Chem . 1996 May; 271(21):12117-20. PMID: 8647799
No abstract available.
9.
Manzella S, Dharmesh S, Beranek M, Swanson P, Baenziger J
J Biol Chem . 1995 Sep; 270(37):21665-71. PMID: 7545167
The circulatory half-life of the mammalian glycoprotein hormone lutropin is controlled by its unique Asn-linked oligosaccharides, which terminate with the sequence SO4-4-GalNAc beta 1,4GlcNAc. A cluster of basic amino acids...
10.
Hooper L, Beranek M, Manzella S, Baenziger J
J Biol Chem . 1995 Mar; 270(11):5985-93. PMID: 7890728
Differential expression of glycosyltransferases has the potential to generate functionally distinct glycoforms of otherwise identical proteins. We have previously demonstrated the presence of unique oligosaccharides terminating with GalNAc-4-SO4 on the...