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S L Mader

Explore the profile of S L Mader including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 246
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Recent Articles
1.
Komers R, Lindsley J, Oyama T, Schutzer W, Reed J, Mader S, et al.
J Clin Invest . 2001 Apr; 107(7):889-98. PMID: 11285308
Prostaglandins (PGs) generated by the enzyme cyclooxygenase (COX) have been implicated in the pathological renal hemodynamics and structural alterations in diabetes mellitus, but the role of individual COX isoenzymes in...
2.
Schutzer W, Reed J, Bliziotes M, Mader S
Am J Physiol Regul Integr Comp Physiol . 2001 Feb; 280(3):R897-903. PMID: 11171671
The age-related decline in beta-adrenergic receptor (beta-AR)-mediated vasorelaxation is associated with desensitization of beta-ARs without significant downregulation. The primary mode of this homologous beta-AR desensitization, in general, is via G...
3.
Schutzer W, Xue H, Reed J, Roullet J, Anderson S, Mader S
Am J Physiol Heart Circ Physiol . 2000 Nov; 279(6):H2807-14. PMID: 11087235
beta-Adrenergic receptor (beta-AR)-mediated (cAMP-dependent) vasorelaxation declines with advancing age. It has been shown that angiotensin II (ANG II), a potent vasoconstrictor, enhances cAMP-mediated vasorelaxation. Therefore, we questioned whether ANG II...
4.
Schutzer W, Watts V, Chapman J, Cumbay M, Neve K, Neve R, et al.
Clin Exp Pharmacol Physiol . 2000 Mar; 27(1-2):9-13. PMID: 10696522
1. Decline in beta-adrenoceptor (beta-AR)-mediated function occurs with increasing age, as well as in multiple disease conditions. The mechanisms responsible for this decline include alterations in beta-AR itself, beta-AR coupling...
5.
Chapman J, Schutzer W, Watts V, Mader S
J Gerontol A Biol Sci Med Sci . 1999 Apr; 54(4):B154-9. PMID: 10219003
Beta-adrenergic-mediated vasorelaxation declines with maturation and aging. Available data suggest that impaired stimulatory G-protein function could explain this deficit. We have previously found a loss of cholera toxin (CT)-stimulated adenosine...
6.
Lowenthal D, Flannery M, Mader S, Nelson Jr R
Geriatrics . 1998 Oct; 53 Suppl 2:S4-28. PMID: 9789482
No abstract available.
7.
Mader S, Alley P
Mech Ageing Dev . 1998 May; 101(1-2):111-8. PMID: 9593317
Blood vessels from aged animals and humans have impaired relaxation and cAMP production to beta-adrenergic stimulation. Direct activators of adenylyl cyclase (AC) such as forskolin are not affected. We hypothesized...
8.
Mader S, Downing C, Swebjka P
J Gerontol A Biol Sci Med Sci . 1996 Mar; 51(2):B111-6. PMID: 8612094
Blood vessels from aged animals and humans have impaired relaxation to beta-adrenergic stimulation. We hypothesized that a loss of stimulatory G protein (Gs) or an increase in inhibitory G proteins...
9.
Martin K, Walsh K, Mader S
Gene . 1994 May; 142(2):275-8. PMID: 8194764
E-box elements, with the CANNTG sequence motif, occur in numerous promoters and enhancers. We evaluated the tissue-specific expression properties of the paired murine E-box element from the mouse muscle creatine...
10.
Gualberto A, Lepage D, Pons G, Mader S, Park K, Atchison M, et al.
Mol Cell Biol . 1992 Sep; 12(9):4209-14. PMID: 1508214
The rapid, transient induction of the c-fos proto-oncogene by serum growth factors is mediated by the serum response element (SRE). The SRE shares homology with the muscle regulatory element (MRE)...