S L Lowe
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Explore the profile of S L Lowe including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
357
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Recent Articles
1.
Lowe S, Duggan Evans C, Shcherbinin S, Cheng Y, Willis B, Gueorguieva I, et al.
J Prev Alzheimers Dis
. 2021 Sep;
8(4):414-424.
PMID: 34585215
Background: Donanemab (LY3002813) is an IgG1 antibody directed at an N‑terminal pyroglutamate of amyloid beta epitope that is present only in brain amyloid plaques. Objectives: To assess effects of donanemab...
2.
Lowe S, Adrian C, Ouporov I, Waingeh V, Thomasson K
Biopolymers
. 2003 Dec;
70(4):456-70.
PMID: 14648757
Previous Brownian dynamics (BD) simulations identified specific basic residues on fructose-1,6-bisphophate aldolase (aldolase) (I. V. Ouporov et al., Biophysical Journal, 1999, Vol. 76, pp. 17-27) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (I....
3.
Lowe S, Pandey R, Czlapinski J, Kie-Adams G, Hoffmann M, Thomasson K, et al.
J Pept Res
. 2003 Feb;
61(4):189-201.
PMID: 12605604
Cyclo(l-Pro)3 (CP3) is a synthetic peptide created to model cis and torsionally strained peptide bonds that also exhibits a strong distinctive UV circular dichroic (CD) spectrum. Circular dichroic spectra were...
4.
Norris J, Hyer M, Voelkel-Johnson C, Lowe S, Rubinchik S, Dong J
Curr Gene Ther
. 2002 Jul;
1(1):123-36.
PMID: 12109135
Prostate cancer is the second leading cause of cancer death in the United States. Treatment options for confined disease are generally successful in prolonging life but long-term cures (10-15 years)...
5.
Lowe S, Rubinchik S, Honda T, McDonnell T, Dong J, Norris J
Gene Ther
. 2001 Sep;
8(18):1363-71.
PMID: 11571575
In prostate carcinoma, overexpression of the anti-apoptotic gene Bcl-2 has been found to be associated with resistance to therapies including radiation and androgen ablation. Restoring the balance of Bcl-2 family...
6.
Ouporov I, Knull H, Lowe S, Thomasson K
J Mol Recognit
. 2001 Feb;
14(1):29-41.
PMID: 11180560
Brownian dynamics (BD) was used to simulate the binding of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to G- and F-actin. High-resolution three-dimensional models (X-ray and homology built) of the proteins were used in...
7.
Bui T, Levy E, Subramaniam V, Lowe S, Hong W
Genomics
. 1999 Apr;
57(2):285-8.
PMID: 10198168
Transport of proteins along the exocytotic pathway is primarily achieved by vesicular intermediates. Two proteins, Golgi SNAREs of 27 kDa, GS27, and of 28 kDa, GS28 (HGMW-approved nomenclature GOSR2 and...
8.
Wong S, Xu Y, Zhang T, Griffiths G, Lowe S, Subramaniam V, et al.
Mol Biol Cell
. 1999 Jan;
10(1):119-34.
PMID: 9880331
Syntaxin 1, synaptobrevins or vesicle-associated membrane proteins, and the synaptosome-associated protein of 25 kDa (SNAP-25) are key molecules involved in the docking and fusion of synaptic vesicles with the presynaptic...
9.
Lowe S, Peter F, Subramaniam V, Wong S, Hong W
Nature
. 1997 Dec;
389(6653):881-4.
PMID: 9349823
In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and delivers them after covalent modification to their destination in the cell. These proteins move...
10.
Lowe S
J Med Ethics
. 1997 Jun;
23(3):154-8; discussion 161-3.
PMID: 9220327
It is widely accepted now that a patient's right to refuse treatment extends to circumstances in which the exercise of that right may lead to the patient's death. However, it...