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S L Edwards

Explore the profile of S L Edwards including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 907
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Recent Articles
1.
French J, Edwards S
Trends Genet . 2020 Aug; 36(11):880-891. PMID: 32741549
The genetic basis of disease has largely focused on coding regions. However, it has become clear that a large proportion of the noncoding genome is functional and harbors genetic variants...
2.
Emmerson S, Mukherjee S, Melendez-Munoz J, Cousins F, Edwards S, Karjalainen P, et al.
Biomaterials . 2019 Oct; 225:119495. PMID: 31606680
The widespread use of synthetic transvaginal polypropylene mesh for treating Pelvic Organ Prolapse (POP) has been curtailed due to serious adverse effects highlighted in 2008 and 2011 FDA warnings and...
3.
Wronski A, Sandhu G, Milevskiy M, Brewster B, Bridge J, Shewan A, et al.
Oncogenesis . 2016 Apr; 5:e218. PMID: 27043663
Depletion of Brca1 leads to defects in mouse mammary gland development and mammary tumors in humans and mice. To explore the role of microRNAs (miRNAs) in this process, we examined...
4.
Edwards S, Ulrich D, White J, Su K, Rosamilia A, Ramshaw J, et al.
Acta Biomater . 2014 Dec; 13:286-94. PMID: 25462845
Use of synthetic clinical meshes in pelvic organ prolapse (POP) repair can lead to poor mechanical compliance in vivo, as a result of a foreign body reaction leading to excessive...
5.
Lau Y, Affleck A, Edwards S, Hogg F, Laube S
Dermatol Online J . 2013 Sep; 19(9):19612. PMID: 24050287
Dermatofibrosarcoma protuberans (DFSP), a rare medium grade sarcoma, occasionally occurs in childhood and is even more rarely present at birth. In children, the clinical appearance may be mistaken for a...
6.
Quigley A, Bulluss K, Kyratzis I, Gilmore K, Mysore T, Schirmer K, et al.
J Neural Eng . 2013 Jan; 10(1):016008. PMID: 23283383
Injury to nerve tissue in the peripheral nervous system (PNS) results in long-term impairment of limb function, dysaesthesia and pain, often with associated psychological effects. Whilst minor injuries can be...
7.
Edwards S, Werkmeister J
J Biomed Mater Res A . 2012 Jun; 100(12):3326-31. PMID: 22733655
Polyetheretherketone (PEEK) is a high performance polymer, with high melting temperature and high resistance to wear. PEEK biomedical devices are typically manufactured to produce nonflexible structures. In this study, we...
8.
Smart C, Wronski A, French J, Edwards S, Asselin-Labat M, Waddell N, et al.
Oncogene . 2010 Dec; 30(13):1597-607. PMID: 21132007
Disruption of the breast cancer susceptibility gene Brca1 results in defective lobular-alveolar development in the mammary gland and a predisposition to breast tumourigenesis in humans and in mice. Recent evidence...
9.
Edwards S
J Natl Med Assoc . 2010 Oct; 6(2):91. PMID: 20891403
No abstract available.
10.
Edwards S, Weakley J, Diamanduros A, Claiborne J
J Fish Biol . 2010 Aug; 76(2):415-26. PMID: 20738718
In the current study, reverse-transcription polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends (RACE) PCR were used to clone full-length putative Na(+)-H(+) exchanger isoforms (NHE2a) cDNA from the...