S K Akiyama
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Explore the profile of S K Akiyama including associated specialties, affiliations and a list of published articles.
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84
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3092
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Recent Articles
1.
Akiyama S
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 10:Unit 10.6.
PMID: 18228300
This unit describes the purification of extracellular vitronectin from plasma by a series of affinity chromatography steps. First plasma is depleted of fibronectin and other heparin-binding proteins; the sample is...
2.
Akiyama S
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 10:Unit 10.5.
PMID: 18228299
This unit describes the purification of the multifunctional adhesive glycoprotein fibronectin from plasma or of cell-derived fibronectin from cell surfaces and from conditioned medium. Fibronectin can be used in cell...
3.
Whittard J, Akiyama S
J Cell Sci
. 2001 Oct;
114(Pt 18):3265-72.
PMID: 11591815
Integrin receptor activation is an important regulatory mechanism for cell-substrate and cell-cell adhesion. In this study, we explore a signaling pathway activated by mAb 12G10, an antibody that can activate...
4.
Palmantier R, George M, Akiyama S, Wolber F, Olden K, Roberts J
Cancer Res
. 2001 Apr;
61(6):2445-52.
PMID: 11289113
We have investigated the effects of various fatty acids (FAs) on integrin-mediated MDA-MB-435 breast carcinoma cell adhesion to type IV collagen (collagen IV) in vitro. Arachidonic acid (AA) and linoleic...
5.
Whittard J, Akiyama S
Exp Cell Res
. 2001 Feb;
263(1):65-76.
PMID: 11161706
Integrins are highly regulated receptors that can function in both cell-substrate and cell-cell adhesion. We have found that the activating anti-beta1 mAb, 12G10, can specifically and rapidly induce both cell-substrate...
6.
Paine E, Palmantier R, Akiyama S, Olden K, Roberts J
J Biol Chem
. 2001 Feb;
275(15):11284-90.
PMID: 10753939
Adhesion of metastatic human mammary carcinoma MDA-MB-435 cells to the basement membrane protein collagen type IV can be activated by treatment with arachidonic acid. We initially observed that this arachidonic...
7.
Akamatsu M, Aota S, Suwa A, Ueda K, Amachi T, Yamada K, et al.
J Biol Chem
. 1999 Dec;
274(50):35933-7.
PMID: 10585480
Vinexin, a novel protein that plays a key role in cell spreading and cytoskeletal organization, contains three SH3 domains and binds to vinculin through its first and second SH3 domains....
8.
Mueller S, Ghersi G, Akiyama S, Sang Q, Howard L, Nakahara H, et al.
J Biol Chem
. 1999 Aug;
274(35):24947-52.
PMID: 10455171
Invadopodia are membrane extensions of aggressive tumor cells that function in the activation of membrane-bound proteases occurring during tumor cell invasion. We explore a novel and provocative activity of integrins...
9.
Rosfjord E, Maemura M, Johnson M, Torri J, Akiyama S, Woods Jr V, et al.
Exp Cell Res
. 1999 Mar;
248(1):260-71.
PMID: 10094832
Cellular adhesions to other cells and to the extracellular matrix play crucial roles in the malignant progression of cancer. In this study, we investigated the role of protein kinase C...
10.
Kioka N, Sakata S, Kawauchi T, Amachi T, Akiyama S, Okazaki K, et al.
J Cell Biol
. 1999 Jan;
144(1):59-69.
PMID: 9885244
Using the yeast two-hybrid system and an in vitro binding assay, we have identified a novel protein termed vinexin as a vinculin-binding protein. By Northern blotting, we identified two types...