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S Ilangumaran

Explore the profile of S Ilangumaran including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 539
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Recent Articles
1.
Villalobos-Hernandez A, Bobbala D, Kandhi R, Khan M, Mayhue M, Dubois C, et al.
Prostate Cancer Prostatic Dis . 2016 Oct; 20(1):36-47. PMID: 27779203
Background: The suppressor of cytokine signaling 1 (SOCS1) gene is repressed in prostate cancer (PCa) by epigenetic silencing and microRNA miR30d. Increased expression of the SOCS1-targeting miR30d correlates with higher...
2.
Bobbala D, Kandhi R, Chen X, Mayhue M, Bouchard E, Yan J, et al.
Leukemia . 2016 Feb; 30(8):1749-52. PMID: 26876593
No abstract available.
3.
Yeganeh M, Gui Y, Kandhi R, Bobbala D, Tobelaim W, Saucier C, et al.
Oncogene . 2016 Jan; 35(32):4200-11. PMID: 26725321
The SOCS1 gene coding for suppressor of cytokine signaling 1 is frequently repressed in hepatocellular carcinoma (HCC), and hence SOCS1 is considered a tumor suppressor in the liver. However, the...
4.
Gui Y, Yeganeh M, Donates Y, Tobelaim W, Chababi W, Mayhue M, et al.
Oncogene . 2015 Mar; 34(46):5718-28. PMID: 25728680
Suppressor of cytokine signaling 1 (SOCS1) is considered as a tumor suppressor protein in hepatocellular carcinoma (HCC), but the underlying mechanisms remain unclear. Previously, we have shown that SOCS1-deficient hepatocytes...
5.
Chen X, Bobbala D, Rodriguez G, Mayhue M, Chen Y, Ilangumaran S, et al.
Clin Exp Immunol . 2013 Apr; 173(2):184-94. PMID: 23607664
Non-obese diabetic (NOD) mice lacking interleukin (IL)-21 or IL-21 receptor do not develop autoimmune type 1 diabetes (T1D). We have shown recently that IL-21 may promote activation of autoreactive CD8(+)...
6.
Bobbala D, Chen X, Leblanc C, Mayhue M, Stankova J, Tanaka T, et al.
Diabetologia . 2012 Aug; 55(11):3010-20. PMID: 22890824
Aims/hypothesis: IL-15, induced by innate immune stimuli, promotes rheumatoid arthritis and inflammatory bowel disease. However, its role in autoimmune type 1 diabetes is unclear. Our aim is to define the...
7.
Shabaana A, Kulangara K, Semac I, Parel Y, Ilangumaran S, Dharmalingam K, et al.
Cell Mol Life Sci . 2005 Jan; 62(2):179-87. PMID: 15666089
Lipoarabinomannans (LAMs) are major lipoglycans of the mycobacterial envelope and constitute immunodominant epitopes of mycobacteria. In this paper, we show that mannose-capped (ManLAM) and non-mannose-capped (PILAM) mycobacterial lipoglycans insert into...
8.
Narayan N, Ramu G, Ilangumaran S, Desikan K, Muthukaruppan V
Indian J Lepr . 2002 Feb; 73(3):239-46. PMID: 11840596
On the basis of clinical features and bacteriological status, macular skin lesions of nine cases of leprosy were classified as falling within a spectrum between the tuberculoid at one end...
9.
Hoessli D, Ilangumaran S, Soltermann A, Robinson P, Borisch B, Nasir-Ud-Din
Glycoconj J . 2001 Feb; 17(3 -4):191-7. PMID: 11201790
Transmembrane signaling requires modular interactions between signaling proteins, phosphorylation or dephosphorylation of the interacting protein partners and temporary elaboration of supramolecular structures, to convey the molecular information from the cell...
10.
De Sepulveda P, Ilangumaran S, Rottapel R
J Biol Chem . 2000 Apr; 275(19):14005-8. PMID: 10747851
Suppressor of cytokine signaling-1 (SOCS1) is an inducible Src homology 2 (SH2)-containing protein that negatively regulates cytokine and growth factor signaling required during thymic development. Recent evidence indicates that SOCS1...