S I Shimuta
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Explore the profile of S I Shimuta including associated specialties, affiliations and a list of published articles.
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23
Citations
71
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Recent Articles
1.
Rodrigues E, Martin R, Silva R, Nakaie C, Oliveira L, Shimuta S
Regul Pept
. 2013 Jan;
181:37-44.
PMID: 23318500
Mutant forms of kinin B(1) receptor (B(1)R) and analogs of the full agonist des-Arg(9)-bradykinin (DABK) were investigated aiming to verify the importance of selected receptor residues and of each agonist-peptide...
2.
Felipe S, Rodrigues E, Martin R, Paiva A, Pesquero J, Shimuta S
Braz J Med Biol Res
. 2007 Apr;
40(5):649-55.
PMID: 17464426
Previous studies have shown that the vascular reactivity of the mouse aorta differs substantially from that of the rat aorta in response to several agonists such as angiotensin II, endothelin-1...
3.
Motta S, Poletti E, Souza S, Correa S, Jubilut G, Paiva A, et al.
J Pept Res
. 2003 Oct;
62(5):227-32.
PMID: 14531846
Tachyphylaxis, defined as the acute loss of response of some smooth muscles upon repeated stimulations with angiotensin II (Ang II), has been shown to be dependent mainly on the N-terminal...
4.
Shimuta S, Barbosa A, Borges A, Paiva T
Immunopharmacology
. 1999 Dec;
45(1-3):63-7.
PMID: 10614991
RMP-7 is a bradykinin (BK) agonist designed to be resistant to kininases such as angiotensin-converting enzyme (ACE). Pharmacological assays were performed with RMP-7 in isolated guinea-pig ileum and rat mesenteric...
5.
Zalcberg H, Assimomytis N, Magafa V, Cordopatis P, Shimuta S
J Pept Res
. 1999 Jul;
53(6):678-81.
PMID: 10408343
Angiotensin II (AII) analogs bearing n-Leu, Met or S-substituted groups for cysteine at position 5 were studied regarding their agonistic and tachyphylactic properties. It was shown that these analogs lowered...
6.
Shimuta S, Borges A, Prioste R, Paiva T
Eur J Pharmacol
. 1999 Mar;
367(1):59-66.
PMID: 10082265
Ca2+ pathways activated by angiotensin II and carbachol were evaluated in the circular muscle of the guinea-pig ileum by recording mechanical and electrical activities. Transient contractions induced by angiotensin II...
7.
Han H, Shimuta S, Kanashiro C, Oliveira L, Han S, Paiva A
Mol Endocrinol
. 1998 Jun;
12(6):810-4.
PMID: 9626656
The role of the external third of helix VI of the angiotensin II (AII) AT1 receptor for the interaction with its ligand and for the subsequent signal transduction was investigated...
8.
Kanashiro C, Paiva T, Paiva A, Prioste R, Aboulafia J, Shimuta S
J Pharmacol Exp Ther
. 1995 Dec;
275(3):1543-50.
PMID: 8531127
Angiotensin II (AII) tachyphylaxis occurs in the guinea pig ileum, but is not induced by analogs lacking the N-terminal amino group or the Arg2 guanidino group. Both AII and Lys2AII...
9.
Shimuta S, Kanashiro C, Ferreira A, Oshiro M, Paiva T, Paiva A
Naunyn Schmiedebergs Arch Pharmacol
. 1993 Apr;
347(4):425-31.
PMID: 8510770
Simultaneous recordings of the tension and intracellular Ca2+ concentration of guinea-pig ileum longitudinal smooth muscle strips, as well as 24Na+ and 45Ca2+ influx measurements in cultured myocytes from the same...
10.
Shimuta S, Kanashiro C, Oshiro M, Paiva T, Paiva A
J Pharmacol Exp Ther
. 1990 Jun;
253(3):1215-21.
PMID: 2359022
The effects of angiotensin II (ANG) on Na+ and Ca++ fluxes in cultured intestinal smooth muscle cells from the guinea pig ileum were studied and correlated with the contraction and...