S H Rosenberg
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Explore the profile of S H Rosenberg including associated specialties, affiliations and a list of published articles.
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51
Citations
748
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Recent Articles
1.
Leverson J, Zhang H, Chen J, Tahir S, Phillips D, Xue J, et al.
Cell Death Dis
. 2015 Jan;
6:e1590.
PMID: 25590800
The anti-apoptotic protein MCL-1 is a key regulator of cancer cell survival and a known resistance factor for small-molecule BCL-2 family inhibitors such as ABT-263 (navitoclax), making it an attractive...
2.
Lefkowitz W, Rosenberg S
J Perinatol
. 2008 Nov;
28(12):837-40.
PMID: 19034291
No abstract available.
3.
Zhang H, Nimmer P, Tahir S, Chen J, Fryer R, Hahn K, et al.
Cell Death Differ
. 2007 Jan;
14(5):943-51.
PMID: 17205078
Platelets are relatively short-lived, anucleated cells that are essential for proper hemostasis. The regulation of platelet survival in the circulation remains poorly understood. The process of platelet activation and senescence...
4.
Szczepankiewicz B, Liu G, Jae H, Tasker A, Gunawardana I, von Geldern T, et al.
J Med Chem
. 2001 Dec;
44(25):4416-30.
PMID: 11728187
During a screen for compounds that could inhibit cell proliferation, a series of new tubulin-binding compounds was identified with the discovery of oxadiazoline 1 (A-105972). This compound showed good cytotoxic...
5.
Liu X, Shi Y, Han E, Chen Z, Rosenberg S, Giranda V, et al.
Neoplasia
. 2001 Sep;
3(4):278-86.
PMID: 11571628
The serine/threonine kinases, Akt1/PKBalpha, Akt2/PKBbeta, and Akt3/PKBgamma, play a critical role in preventing cancer cells from undergoing apoptosis. However, the function of individual Akt isoforms in the tumorigenicity of cancer...
6.
Tahir S, Han E, Credo B, Jae H, Pietenpol J, Scatena C, et al.
Cancer Res
. 2001 Jul;
61(14):5480-5.
PMID: 11454695
Drug resistance is a prevalent problem in the treatment of neoplastic disease, and the effectiveness of many clinically useful drugs is limited by the fact that they are substrates for...
7.
Banks D, Plescia J, Altieri D, Chen J, Rosenberg S, Zhang H, et al.
Blood
. 2001 Feb;
96(12):4002-3.
PMID: 11186274
No abstract available.
8.
Chen J, Wu W, Tahir S, Kroeger P, Rosenberg S, Cowsert L, et al.
Neoplasia
. 2000 Aug;
2(3):235-41.
PMID: 10935509
Survivin, a member of the inhibitor of apoptosis protein (IAP) family, is detected in most common human cancers but not in adjacent normal cells. Previous studies suggest that survivin associates...
9.
Han E, Gehrke L, Tahir S, Credo R, Cherian S, Sham H, et al.
Eur J Cancer
. 2000 Aug;
36(12):1565-71.
PMID: 10930805
Beta(beta)-tubulin isotype variation has recently been implicated in the modulation of resistance to paclitaxel in human lung cancer cells and in primary human ovarian tumour samples. Whether alpha-tubulin is involved...
10.
Tahir S, Kovar P, Rosenberg S, Ng S
Biotechniques
. 2000 Jul;
29(1):156-60.
PMID: 10907090
We have developed a rapid [3H]colchicine competition-binding scintillation proximity assay (SPA) to evaluate antimitotic compounds that bind to the colchicine-binding site on tubulin. The premise of our assay is that...