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S F Francom

Explore the profile of S F Francom including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 97
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Recent Articles
1.
Fleishaker J, Francom S, Herman B, Knuth D, Azie N
Clin Pharmacol Ther . 2001 Sep; 70(3):261-9. PMID: 11557914
Objective: The effect of reboxetine on electrocardiographic parameters, particularly the QTc interval, was assessed in 20 healthy subjects (15 male, 5 female). Methods: In a 5-way crossover study, subjects received...
2.
Fleishaker J, Pearson L, Knuth D, Gomez-Mancilla B, Francom S, McIntosh M, et al.
Int J Clin Pharmacol Ther . 1999 Oct; 37(10):487-92. PMID: 10543315
Objectives: The objectives of this study were to characterize the safety, tolerability and pharmacokinetics of a single, oral dose of PNU-142633F escalating over the range of 1.0 mg to 100...
3.
BROOKS C, Chene B, Klott K, Busboom S, Francom S
Am J Rhinol . 1997 Mar; 11(2):117-22. PMID: 9129753
This study examined the effects of low dose systemic corticoid (methylprednisolone, MP), standard dose antihistamine (terfenadine, TF) or the combination on response to out-of-season acute allergen challenge. We feel that...
4.
Hughes Jr G, Antal E, Locker P, Francom S, Adams W, Jacobs Jr E
Crit Care Med . 1996 May; 24(5):756-64. PMID: 8706450
Objective: To evaluate the physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier of bovine origin. Design: Randomized, single-blind, placebo-controlled, dose-escalation study. Setting: The Upjohn Research Clinics (Kalamazoo, MI). Subjects:...
5.
Hughes G, Francom S, Antal E, Adams W, Locker P, Yancey E, et al.
Ann Emerg Med . 1996 Feb; 27(2):164-9. PMID: 8629746
Study Objective: Hemoglobin-based oxygen carrier 201 (HBOC-201) is a polymerized hemoglobin of bovine origin being developed for use in hemorrhage during surgery or trauma. Pulse oximetry is commonly used in...
6.
Hughes Jr G, Yancey E, Albrecht R, Locker P, Francom S, Orringer E, et al.
Clin Pharmacol Ther . 1995 Oct; 58(4):434-43. PMID: 7586936
Objective: The objective of this study was to evaluate the exercise capacity of subjects given an autologous transfusion or a polymerized bovine hemoglobin solution to define the pharmacodynamics and pharmacokinetics...
7.
Locker P, Jungbluth G, Francom S, Hughes Jr G
Clin Pharmacol Ther . 1995 Jan; 57(1):73-88. PMID: 7828385
Objective: To determine the effects of lifibrol on serum lipids in adult patients with primary hypercholesterolemia. Methods: These were two double-blind, randomized placebo-controlled studies. Each patient in each study had...
8.
BROOKS C, Karl K, Francom S
Transplantation . 1994 Nov; 58(10):1135-7. PMID: 7974723
No abstract available.
9.
Hughes Jr G, Ringer T, Francom S, Means L, DeLoof M
Am J Med Sci . 1994 Jul; 308(1):16-22. PMID: 8010332
Beta-carotene in doses of up to 300 mg daily raises high-density lipoprotein cholesterol levels within 2 to 4 weeks in healthy subjects. The authors, in this study, investigate the short-term...
10.
Hughes Jr G, DeSmith V, Locker P, Francom S
J Lab Clin Med . 1994 Feb; 123(2):290-8. PMID: 8301206
The purpose of this study was to evaluate the effects of phlebotomy of 500 or 750 ml of whole blood followed by isovolemic hemodilution or autologous transfusion on hemodynamic, hematologic,...