S E Harding
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Explore the profile of S E Harding including associated specialties, affiliations and a list of published articles.
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200
Citations
2185
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Recent Articles
1.
Dvinskikh L, Sparks H, Brito L, MacLeod K, Harding S, Dunsby C
Sci Rep
. 2023 Feb;
13(1):3342.
PMID: 36849727
Improving cardiac function through stem-cell regenerative therapy requires functional and structural integration of the transplanted cells with the host tissue. Visualizing the electromechanical interaction between native and graft cells necessitates...
2.
Lyon A, Babalis D, Morley-Smith A, Hedger M, Suarez Barrientos A, Foldes G, et al.
Gene Ther
. 2020 Jul;
27(12):579-590.
PMID: 32669717
The SERCA-LVAD trial was a phase 2a trial assessing the safety and feasibility of delivering an adeno-associated vector 1 carrying the cardiac isoform of the sarcoplasmic reticulum calcium ATPase (AAV1/SERCA2a)...
3.
Machuki J, Zhang H, Harding S, Sun H
Acta Physiol (Oxf)
. 2017 Oct;
222(2).
PMID: 28994249
Oestrogen receptors (ERs) and β-adrenergic receptors (βARs) play important roles in the cardiovascular system. Moreover, these receptors are expressed in cardiac myocytes and vascular tissues. Numerous experimental observations support the...
4.
Roca-Alonso L, Castellano L, Mills A, Dabrowska A, Sikkel M, Pellegrino L, et al.
Cell Death Dis
. 2015 May;
6:e1754.
PMID: 25950484
The use of anthracyclines such as doxorubicin (DOX) has improved outcome in cancer patients, yet associated risks of cardiomyopathy have limited their clinical application. DOX-associated cardiotoxicity is frequently irreversible and...
5.
Rees P, Davidson S, Harding S, McGregor C, Elliot P, Yellon D, et al.
Cardiovasc Drugs Ther
. 2013 Feb;
27(3):235-7.
PMID: 23380984
No abstract available.
6.
Johnson W, Katugampola S, Able S, Napier C, Harding S
Life Sci
. 2012 Jan;
90(9-10):328-36.
PMID: 22261303
Aims: Phosphodiesterases (PDEs) are key enzymes controlling cAMP and cGMP levels and spatial distribution within cardiomyocytes. Despite the clinical importance of several classes of PDE inhibitor there has not been...
7.
Quinn T, Granite S, Allessie M, Antzelevitch C, Bollensdorff C, Bub G, et al.
Prog Biophys Mol Biol
. 2011 Jul;
107(1):4-10.
PMID: 21745496
Cardiac experimental electrophysiology is in need of a well-defined Minimum Information Standard for recording, annotating, and reporting experimental data. As a step towards establishing this, we present a draft standard,...
8.
Molina-Garcia A, Harding S, Diaz F, de la Torre J, Rowitch D, Perham R
Biophys J
. 2009 May;
63(5):1293-8.
PMID: 19431854
(a) Bacteriophage fd is a filamentous virus that has previously been well characterized. (b) Earlier work using point mutagenesis indicated that a lysine residue at position 48 in the major...
9.
Harding S
Biophys J
. 2009 May;
51(4):673-80.
PMID: 19431695
A general method for modeling macromolecular shape in solution is described involving measurements of viscosity, radius of gyration, and the second thermodynamic virial coefficient. The method, which should be relatively...
10.
Yadav N, Morris G, Harding S, Ang S, Adams G
Endocr Metab Immune Disord Drug Targets
. 2009 Mar;
9(1):1-13.
PMID: 19275677
Diabetes mellitus (diabetes) is suffered by more than 180 million people and is responsible for approximately 2.9 million deaths each year. This mortality rate is expected to increase by 50...