S E Gerchman
Overview
Explore the profile of S E Gerchman including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
555
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0
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Recent Articles
1.
Bonanno J, Edo C, Eswar N, Pieper U, Romanowski M, Ilyin V, et al.
Proc Natl Acad Sci U S A
. 2001 Nov;
98(23):12896-901.
PMID: 11698677
X-ray structures of two enzymes in the sterol/isoprenoid biosynthesis pathway have been determined in a structural genomics pilot study. Mevalonate-5-diphosphate decarboxylase (MDD) is a single-domain alpha/beta protein that catalyzes the...
2.
Zharkov D, Gilboa R, Yagil I, Kycia J, Gerchman S, Shoham G, et al.
Biochemistry
. 2000 Dec;
39(48):14768-78.
PMID: 11101292
MutY participates in the repair of oxidatively damaged DNA by excising adenine from dA:dG and dA:8-oxodG mispairs; this DNA glycosylase can be cross-linked to DNA through Lys-142. We have investigated...
3.
Zharkov D, Rosenquist T, Gerchman S, Grollman A
J Biol Chem
. 2000 Jul;
275(37):28607-17.
PMID: 10884383
Genomic DNA is prone to oxidation by reactive oxygen species. A major product of DNA oxidation is the miscoding base 8-oxoguanine (8-oxoG). The mutagenic effects of 8-oxoG in mammalian cells...
4.
Rieger R, McTigue M, Kycia J, Gerchman S, Grollman A, Iden C
J Am Soc Mass Spectrom
. 2000 Jun;
11(6):505-15.
PMID: 10833024
Electrospray mass spectrometry techniques were used to characterize components of the active site in Endonuclease VIII by identifying the amino acid sequence and the binding site for a tryptic peptide...
5.
McCutcheon J, Agrawal R, Philips S, Grassucci R, Gerchman S, Clemons Jr W, et al.
Proc Natl Acad Sci U S A
. 1999 Apr;
96(8):4301-6.
PMID: 10200257
The location of translational initiation factor IF3 bound to the 30S subunit of the Thermus thermophilus ribosome has been determined by cryoelectron microscopy. Both the 30S.IF3 complex and control 30S...
6.
Zhou Y, Gerchman S, Ramakrishnan V, Travers A, Muyldermans S
Nature
. 1998 Oct;
395(6700):402-5.
PMID: 9759733
It is essential to identify the exact location of the linker histone within nucleosomes, the fundamental packing units of chromatin, in order to understand how condensed, transcriptionally inactive chromatin forms....
7.
Goytisolo F, Gerchman S, Yu X, Rees C, Graziano V, Ramakrishnan V, et al.
EMBO J
. 1996 Jul;
15(13):3421-9.
PMID: 8670844
The nature of the complexes of histones H1 and H5 and their globular domains (GH1 and GH5) with DNA suggested two DNA-binding sites which are likely to be the basis...
8.
Graziano V, Gerchman S, Schneider D, Ramakrishnan V
Basic Life Sci
. 1996 Jan;
64:127-36.
PMID: 9031508
We have been engaged in studies of the structure and condensation of chromatin into the 30 nm filament using small-angle neutron scattering. We have also used deuterated histone H1 to...
9.
Ramakrishnan V, Davies C, Gerchman S, Golden B, Hoffmann D, Jaishree T, et al.
Biochem Cell Biol
. 1995 Nov;
73(11-12):979-86.
PMID: 8722013
After a long hiatus, the pace of determination of the structures of ribosomal proteins has accelerated dramatically. We discuss here the structures of five ribosomal proteins from Bacillus stearothermophilus: S5,...
10.
Kycia J, Biou V, Shu F, Gerchman S, Graziano V, Ramakrishnan V
Biochemistry
. 1995 May;
34(18):6183-7.
PMID: 7742323
We show that translation initiation factor IF3 can be split into two fragments of nearly equal size by the Escherichia coli outer membrane protease omptin. Circular dichroism and small-angle neutron...