S Candeias
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Explore the profile of S Candeias including associated specialties, affiliations and a list of published articles.
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15
Citations
265
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Recent Articles
1.
Candeias S, Pons B, Viau M, Caillat S, Sauvaigo S
Mutat Res
. 2010 Oct;
694(1-2):53-9.
PMID: 20969882
The well established toxicity of cadmium and cadmium compounds results from their additive effects on several key cellular processes, including DNA repair. Mammalian cells have evolved several biochemical pathways to...
2.
Durum S, Candeias S, Nakajima H, Leonard W, Baird A, Berg L, et al.
J Exp Med
. 1998 Dec;
188(12):2233-41.
PMID: 9858510
VDJ recombination of T cell receptor and immunoglobulin loci occurs in immature lymphoid cells. Although the molecular mechanisms of DNA cleavage and ligation have become more clear, it is not...
3.
Gallagher M, Candeias S, MARTINON C, Borel E, Malissen M, Marche P, et al.
Eur J Immunol
. 1998 Dec;
28(11):3878-85.
PMID: 9842931
The CD3 signaling complex is required for cell surface expression and selection of both alphabeta and gammadelta TCR. In this study we analyzed TCRD transcripts in both wild-type and CD3-epsilon-deficient...
4.
Jouvin-Marche E, Aude-Garcia C, Candeias S, Borel E, Gahery-Segard H, Cazenave P, et al.
Eur J Immunol
. 1998 Apr;
28(3):818-27.
PMID: 9541576
The genes coding for TCR alpha and delta chains share the same genetic locus (TCRA/D). The rules governing the utilization of a V gene with the alpha and delta chains...
5.
Kitazawa H, Muegge K, Badolato R, Wang J, Fogler W, Ferris D, et al.
J Immunol
. 1997 Sep;
159(5):2259-64.
PMID: 9278314
IL-7, a cytokine produced by thymic epithelium, was shown to induce adhesion of murine thymocytes to gelatin-coated membranes. A major binding component of gelatin was identified as fibronectin. IL-7-induced adhesion...
6.
Candeias S, Peschon J, Muegge K, Durum S
Immunol Lett
. 1997 Jun;
57(1-3):9-14.
PMID: 9232418
T-cell receptor (TCR) genes need to be rearranged by a site specific-VDJ recombinase before they are expressed. This process, initiated in CD44+25+ thymocytes, takes place during the early stage of...
7.
8.
Candeias S, Muegge K, Durum S
J Exp Med
. 1996 Nov;
184(5):1919-26.
PMID: 8920879
The site-specific V(D)J recombination reaction necessary to assemble the genes coding for immunoglobulin (Ig) and T cell receptor (TCR) variable regions is initiated by a precise double strand cut at...
9.
Jarvis C, Geiman T, Osipovich O, Akella U, Candeias S, Nathan I, et al.
Gene
. 1996 Mar;
169(2):203-7.
PMID: 8647447
DNA helicases (Hel) play a role in a number of processes involving DNA strand separation, including replication, repair, recombination and transcription. Rearrangement of receptor genes, which occurs in immature lymphocytes,...
10.
Carlsson L, Candeias S, Staerz U, Keller G
Eur J Immunol
. 1995 Aug;
25(8):2308-17.
PMID: 7664793
We have isolated four distinct fetal liver (FL) populations based on the expression of AA4.1 and the low-affinity Fc gamma receptors type II and III (Fc gamma RII/III), and characterized...