S C Land
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Explore the profile of S C Land including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
753
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Recent Articles
1.
Malchow R, Land S, Patel L, Smith P
Biol Bull
. 2017 Jun;
193(2):231-232.
PMID: 28575613
No abstract available.
2.
Preston R, Philp A, Claessens T, Gijezen L, Dydensborg A, Dunlop E, et al.
Oncogene
. 2010 Nov;
30(10):1159-73.
PMID: 21057536
Under conditions of reduced tissue oxygenation, hypoxia-inducible factor (HIF) controls many processes, including angiogenesis and cellular metabolism, and also influences cell proliferation and survival decisions. HIF is centrally involved in...
3.
Scott C, Walker D, Cwiklinski E, Tait C, Tee A, Land S
Am J Physiol Lung Cell Mol Physiol
. 2010 Jul;
299(4):L455-71.
PMID: 20622121
Lung development requires coordinated signaling between airway and vascular growth, but the link between these processes remains unclear. Mammalian target of rapamycin complex-1 (mTORC1) can amplify hypoxia-inducible factor-1α (HIF-1α) vasculogenic...
4.
Rae C, Cherry J, Land F, Land S
Biochem Biophys Res Commun
. 2006 Aug;
349(1):416-25.
PMID: 16934757
Inflammation induces premature maturation of the fetal lung but the signals causing this effect remain unclear. We determined if nitric oxide (NO) synthesis, evoked by Escherichia coli lipopolysaccharide (LPS, 2...
5.
Land S, Rae C
Am J Physiol Cell Physiol
. 2005 May;
289(4):C918-33.
PMID: 15901597
Nitric oxide (NO) modulates cellular metabolism by competitively inhibiting the reduction of O2 at respiratory complex IV. The aim of this study was to determine whether this effect could enhance...
6.
Ramminger S, Richard K, Inglis S, Land S, Olver R, Wilson S
Am J Physiol Lung Cell Mol Physiol
. 2004 Apr;
287(2):L411-9.
PMID: 15090368
Treating H441 cells with dexamethasone raised the abundance of mRNA encoding the epithelial Na(+) channel alpha- and beta-subunits and increased transepithelial ion transport (measured as short-circuit current, I(sc)) from <4...
7.
Haddad J, Land S
Br J Pharmacol
. 2002 Jan;
135(2):520-36.
PMID: 11815388
Redox and ROS regulation of MAPK-mediated TNF-alpha biosynthesis is not well characterized. It was hypothesized that the involvement of the MAPK pathway in regulating LPS-mediated TNF-alpha secretion is redox-dependent, NF-kappaB-sensitive...
8.
Haddad J, Land S
FEBS Lett
. 2001 Sep;
505(2):269-74.
PMID: 11566189
A non-hypoxic, reactive oxygen species (ROS)-sensitive pathway mediating tumor necrosis factor-alpha (TNF-alpha)-dependent regulation of hypoxia-inducible factor-1alpha (HIF-alpha) was investigated in vitro. TNF-alpha mediated the translocation of HIF-1alpha, associated with up-regulating...
9.
Jovanovic S, Land S, Olver R, Wilson S
Biochem Biophys Res Commun
. 2001 Aug;
286(3):622-7.
PMID: 11511105
Imposing hypoxia (P(O(2)) = 23 mmHg) upon A549 cells elicited increased G(amil) although previous work had predicted a fall in this parameter. G(amil) appeared to be dependent upon glucocorticoid-driven gene...
10.
Haddad J, Land S
Biochem Biophys Res Commun
. 2001 Jul;
285(2):267-72.
PMID: 11444836
We have investigated the role that the nuclear factor (NF)-kappaB plays in regulating the biosynthesis of tumor necrosis factor (TNF)-alpha, an inflammatory cytokine. Irreversible inhibition of the proteasome complex by...