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S C Aitken

Explore the profile of S C Aitken including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 220
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Recent Articles
1.
Bronze M, Aitken S, Wallis C, Steegen K, Stuyver L, Rinke de Wit T, et al.
J Virol Methods . 2013 Sep; 194(1-2):300-7. PMID: 23994150
HIV-1 RNA viral load is the preferred tool to monitor virological failure during antiretroviral therapy (ART) exposure. Timely detection of virological failure can reduce the prevalence and complexity of HIV-1...
2.
Riegel A, Aitken S, Martin M, Schoenberg D
Endocrinology . 1987 Apr; 120(4):1283-90. PMID: 3030694
Low levels of estrogen receptor (200-500 per cell) are present in the liver of hormonally naive male Xenopus. However, administration of estradiol results in a rapid 2- to 5-fold increase...
3.
Riegel A, Aitken S, Martin M, Schoenberg D
Mol Endocrinol . 1987 Feb; 1(2):160-7. PMID: 3454873
We have previously shown that estrogen administration to male Xenopus laevis results in the posttranscriptional suppression of serum albumin mRNA concurrent with the transcriptional activation of the genes for the...
4.
Aitken S, Lippman M, Kasid A, Schoenberg D
Cancer Res . 1985 Jun; 45(6):2608-15. PMID: 3986799
The growth of MCF-7 cells was arrested by 24 h of isoleucine deprivation. Following replenishment of the medium, the incorporation of uridine and thymidine into trichloroacetic acid-precipitable material began to...
5.
Aitken S, Lippman M
Cancer Res . 1985 Apr; 45(4):1611-20. PMID: 3978629
The effect of estrogens and antiestrogens is examined on three enzymes the activities of which are known to correlate with cell growth. Estrogen treatment increases thymidylate synthetase binding sites up...
6.
Aitken S, Lippman M
Cancer Res . 1983 Oct; 43(10):4681-90. PMID: 6883327
The hormonal regulation of pyrimidine synthesis and utilization is examined in the estrogen-responsive MCF-7 human breast cancer cell line. [14C]Acetate is used as a novel marker in assaying the incorporation...
7.
Cowan K, Goldsmith M, LEVINE R, Aitken S, Douglass E, Clendeninn N, et al.
J Biol Chem . 1982 Dec; 257(24):15079-86. PMID: 7174686
Methotrexate-resistant (MTXR) human breast cancer cells have been obtained which are 1000-fold less sensitive to this drug than the wild type MCF-7 cells from which they were derived. The resistant...
8.
Aitken S, Lippman M
Cancer Res . 1982 May; 42(5):1727-35. PMID: 7066894
Estrogens and anti-estrogens have striking effects on growth of target tissues in vivo. In order to examine these effects in vitro, experimental methods for the rigorous assessment of rates of...
9.
Aitken S, Lal S
Brain Res . 1982 Mar; 257(1):57-64. PMID: 7059846
The functional properties of Type II mechanoreceptor units of the sural nerve of the rabbit have been examined, using controlled mechanical stimuli applied to the skin. The response of Type...
10.
Aitken S, Lal S
Brain Res . 1982 Mar; 257(1):45-56. PMID: 7059845
The functional characteristics and spatial arrangement of Type I mechanosensitive units found in the sural nerve of the anaesthetized rabbit have been investigated. There are approximately 108 Type I units...