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S Aosasa

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Articles 11
Citations 134
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Recent Articles
1.
Takahata R, Ono S, Tsujimoto H, Hiraki S, Aosasa S, Yamamoto J, et al.
Dis Esophagus . 2014 Aug; 29(1):70-8. PMID: 25139532
We herein clarified the time course of changes in the serum high mobility group box chromosomal protein-1 (HMGB-1) concentrations in esophageal cancer patients after esophagectomy, and investigated whether the perioperative...
2.
Ono S, Ueno C, Aosasa S, Tsujimoto H, Seki S, Mochizuki H
Am J Surg . 2002 Jan; 182(5):491-7. PMID: 11754857
Background: After severe sepsis, there is an increase of Th2 cytokine and a decrease in Th1 cytokine that may account for impaired cellular immunity. The aim of this study is...
3.
Ono S, Aosasa S, Tsujimoto H, Ueno C, Mochizuki H
Eur Surg Res . 2001 May; 33(1):33-8. PMID: 11340270
Objective: To investigate age-related changes in the host response to surgical stress. The clinical course, serum interleukin-6 (IL-6) levels, monocyte production of tumor necrosis factor-alpha (TNF-alpha), and monocyte expression of...
4.
Aosasa S, Ono S, Mochizuki H, Tsujimoto H, Ueno C, Matsumoto A
Shock . 2001 Feb; 15(2):101-5. PMID: 11220636
If the inflammatory response becomes excessive or uncontrolled by some stimuli, inappropriate inflammatory responses occur. Monocytes are extremely important cells for regulating the cytokine network and tumor necrosis factor alpha...
5.
Ogle C, Kong F, Guo X, Wells D, Aosasa S, Noel G, et al.
Shock . 2000 Oct; 14(3):392-8; discussion 398-9. PMID: 11028562
The newly identified suppressors of cytokine signaling (SOCS) family of proteins act as intracellular inhibitors of several cytokine signal transduction pathways. Their expression is induced by cytokine activation of the...
6.
Aosasa S, Ono S, Mochizuki H, Tsujimoto H, Osada S, Takayama E, et al.
World J Surg . 1999 Dec; 24(1):10-6. PMID: 10594196
Surgical injury not only induces a systemic endocrine-metabolic response but also influences the function of the leukocytes and endothelial cells leading to various systemic responses. These responses appear to depend...
7.
Aosasa S, Mochizuki H, Yamamoto T, Ono S, Ichikura T
JPEN J Parenter Enteral Nutr . 1999 Sep; 23(5 Suppl):S41-4. PMID: 10483893
Bacterial translocation (BT) is a well-known insult during total parenteral nutrition (TPN) and a high incidence of morbidity has been reported in septic patients receiving TPN. Inflammatory cytokines were shown...
8.
Ono S, Aosasa S, Mochizuki H
Am J Surg . 1999 Feb; 177(1):78-82. PMID: 10037314
Objective: To evaluate the efficacy of gabexate mesilate (GM) in reducing surgical stress after esophagectomy. Methods: In a prospective, randomized, clinical study, 11 patients with squamous cell carcinoma of the...
9.
Aosasa S, Ono S, Seki S, Takayama E, Tadakuma T, Hiraide H, et al.
J Surg Res . 1999 Jan; 80(2):182-7. PMID: 9878311
Background: Endothelial cells (EC) are important for regulating the hemostatic balance of prothrombotic and antithrombotic activities. Proinflammatory cytokines such as tumor necrosis factor-alpha (TNFalpha) play an important role in the...
10.
Seki S, Osada S, Ono S, Aosasa S, Habu Y, Nishikage T, et al.
Infect Immun . 1998 Oct; 66(11):5286-94. PMID: 9784534
Gamma interferon (IFN-gamma), tumor necrosis factor alpha (TNF-alpha), and interleukin-10 (IL-10) production by liver, spleen, lung, peripheral blood mononuclear cells (MNC), and peritoneal exudate cells (PEC) in experimental bacterial peritonitis...