S A Leachman
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Explore the profile of S A Leachman including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
202
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0
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Recent Articles
1.
Petrie T, Larson C, Heath M, Samatham R, Davis A, Berry E, et al.
Skin Health Dis
. 2022 Jun;
1(2):e19.
PMID: 35664971
Background: Many classifiers have been developed that can distinguish different types of skin lesions (e.g., benign nevi, melanoma) with varying degrees of success. However, even successfully trained classifiers may perform...
2.
Harris K, Hull P, Hansen C, Smith F, McLean W, Arbiser J, et al.
Br J Dermatol
. 2011 Jul;
166(1):124-8.
PMID: 21790523
Background: Pachyonychia congenita (PC) is a rare keratin disorder that typically presents with nail dystrophy and focal plantar keratoderma. We present seven cases of PC with transgrediens involvement of the...
3.
Jenkins N, Liu T, Cassidy P, Leachman S, Boucher K, Goodson A, et al.
Oncogene
. 2010 Sep;
30(3):265-74.
PMID: 20838381
Mutations or deletions in the cyclin-dependent kinase inhibitor p16(INK4A) are associated with multiple cancer types, but are more commonly found in melanoma tumors and associated with familial melanoma predisposition. Although...
4.
Pho L, Leachman S
G Ital Dermatol Venereol
. 2010 Mar;
145(1):37-45.
PMID: 20197744
About 5-10% of human cutaneous malignant melanoma is hereditary and known to involve rare germline mutations in highly penetrant, autosomal dominant genes. These genes are important in cell cycle control...
5.
Yan H, Thomas J, Liu T, D Raj , London N, Tandeski T, et al.
Oncogene
. 2006 May;
25(52):6968-74.
PMID: 16702945
The inhibitor of apoptosis gene family member Survivin is highly expressed in most tumors, and appears to be a promising target for cancer therapy. Although a variety of Survivin antagonists...
6.
Pond C, Leachman S, Warters R
Radiat Res
. 2004 May;
161(6):739-45.
PMID: 15161345
In this study, we examined effects of low-dose ionizing radiation on organ cultured human foreskin and, in particular, on the epidermis. Diagnostic, therapeutic, natural environmental and incidental exposures to moderate...
7.
Florell S, Coffin C, Holden J, Zimmermann J, Gerwels J, Summers B, et al.
Mod Pathol
. 2001 Mar;
14(2):116-28.
PMID: 11235903
Few human tumors are collected such that RNA is preserved for molecular analysis. Completion of the Human Genome Project will soon result in the identification of more than 100,000 new...
8.
Leachman S, Tigelaar R, Shlyankevich M, Slade M, Irwin M, Chang E, et al.
J Virol
. 2000 Aug;
74(18):8700-8.
PMID: 10954571
A cottontail rabbit papillomavirus (CRPV) E6 DNA vaccine that induces significant protection against CRPV challenge was used in a superior vaccination regimen in which the cutaneous sites of vaccination were...
9.
Leachman S, Insogna K, Katz L, Ellison A, Milstone L
Arch Dermatol
. 1999 Aug;
135(8):961-5.
PMID: 10456346
Background: Few studies have been done of bone densities in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured bone density and...
10.
Leachman S, Gallagher P, Herring B, McPhaul M, Stull J
J Biol Chem
. 1992 Mar;
267(7):4930-8.
PMID: 1371510
The molecular and biochemical properties of myosin light chain kinases from chicken skeletal and smooth muscle were investigated by recombinant DNA techniques. Deletion of the amino-terminal region of either the...