Ryuta Muromoto
Overview
Explore the profile of Ryuta Muromoto including associated specialties, affiliations and a list of published articles.
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Articles
98
Citations
1052
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Recent Articles
1.
Kagohashi K, Sasaki Y, Ozawa K, Tsuchiya T, Kawahara S, Saitoh K, et al.
J Immunol
. 2024 Feb;
212(6):951-961.
PMID: 38315039
Signal-transducing adaptor protein (STAP)-1 is an adaptor protein that is widely expressed in T cells. In this article, we show that STAP-1 upregulates TCR-mediated T cell activation and T cell-mediated...
2.
Kashiwakura J, Kawahara S, Inagaki I, Inui K, Saitoh K, Kagohashi K, et al.
FEBS Lett
. 2023 Sep;
597(19):2433-2445.
PMID: 37669828
Although signal-transducing adaptor protein-2 (STAP-2) acts in certain immune responses, its role in B cell receptor (BCR)-mediated signals remains unknown. In this study, we have revealed that BCR-mediated signals, cytokine...
3.
Sasaki Y, Saitoh K, Kagohashi K, Ose T, Kawahara S, Kitai Y, et al.
J Immunol
. 2023 Jul;
211(5):755-766.
PMID: 37417746
Signal-transducing adaptor protein-2 (STAP-2) is an adaptor protein that contains pleckstrin and Src homology 2-like domains, as well as a proline-rich region in its C-terminal region. Our previous study demonstrated...
4.
Maemoto T, Kitai Y, Takahashi R, Shoji H, Yamada S, Takei S, et al.
J Biol Chem
. 2022 Nov;
299(1):102724.
PMID: 36410436
Signal-transducing adaptor family member-2 (STAP-2) is an adaptor protein that regulates various intracellular signals. We previously demonstrated that STAP-2 binds to epidermal growth factor receptor (EGFR) and facilitates its stability...
5.
Hashimoto S, Hashimoto A, Muromoto R, Kitai Y, Oritani K, Matsuda T
Cells
. 2022 Aug;
11(16).
PMID: 36010693
Since the time of Rudolf Virchow in the 19th century, it has been well-known that cancer-associated inflammation contributes to tumor initiation and progression. However, it remains unclear whether a collapse...
6.
Saitoh K, Kashiwakura J, Kagohashi K, Sasaki Y, Kawahara S, Sekine Y, et al.
J Immunol
. 2022 Jun;
209(1):57-68.
PMID: 35725273
TCR ligation with an Ag presented on MHC molecules promotes T cell activation, leading to the selection, differentiation, and proliferation of T cells and cytokine production. These immunological events are...
7.
Yamada S, Kitai Y, Tadokoro T, Takahashi R, Shoji H, Maemoto T, et al.
J Immunol
. 2022 Jun;
209(1):171-179.
PMID: 35725272
Damage-associated molecular patterns (DAMPs) contribute to antitumor immunity during cancer chemotherapy. We previously demonstrated that topotecan (TPT), a topoisomerase I inhibitor, induces DAMP secretion from cancer cells, which activates STING-mediated...
8.
Muromoto R, Sato A, Komori Y, Nariya K, Kitai Y, Kashiwakura J, et al.
Biochem Biophys Res Commun
. 2022 May;
613:61-66.
PMID: 35537286
Interleukin-17A (IL-17A) is a cytokine that affects the functions of non-immune cells, including keratinocytes, and thereby amplifies immune responses. An IκB family protein IκB-ζ, encoded by the NFKBIZ gene, mediates...
9.
Kubota A, Terasaki M, Sakuragi Y, Muromoto R, Ikeda-Araki A, Takada H, et al.
Ecotoxicol Environ Saf
. 2022 May;
238:113549.
PMID: 35500401
Benzotriazole UV stabilizers (BUVSs) are widely used as additives in various materials, including plastics, to prevent damage from UV-irradiation. However, despite the extensive usage of BUVSs, information on their toxicological...
10.
Sekine Y, Kikkawa K, Witthuhn B, Kashiwakura J, Muromoto R, Kitai Y, et al.
Int Immunol
. 2022 Feb;
34(6):303-312.
PMID: 35192696
Jak3, a member of the Janus kinase family, is essential for the cytokine receptor common gamma chain (γc)-mediated signaling. During activation of Jak3, tyrosine residues are phosphorylated and potentially regulate...