Ryan Lane
Overview
Explore the profile of Ryan Lane including associated specialties, affiliations and a list of published articles.
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11
Citations
56
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Recent Articles
1.
Kievits A, Duinkerken B, Lane R, de Heus C, van Beijeren Bergen En Henegouwen D, Hoppener T, et al.
Methods Microsc
. 2024 Aug;
1(1):49-64.
PMID: 39119255
Elucidating the 3D nanoscale structure of tissues and cells is essential for understanding the complexity of biological processes. Electron microscopy (EM) offers the resolution needed for reliable interpretation, but the...
2.
Lu Y, Berenson A, Lane R, Guelin I, Li Z, Chen Y, et al.
Life Sci Alliance
. 2024 Jul;
7(10).
PMID: 39013578
Cancer development and progression are generally associated with gene dysregulation, often resulting from changes in the transcription factor (TF) sequence or expression. Identifying key TFs involved in cancer gene regulation...
3.
Lambourne L, Mattioli K, Santoso C, Sheynkman G, Inukai S, Kaundal B, et al.
bioRxiv
. 2024 Apr;
PMID: 38617209
Most human Transcription factors (TFs) genes encode multiple protein isoforms differing in DNA binding domains, effector domains, or other protein regions. The global extent to which this results in functional...
4.
Lu Y, Berenson A, Lane R, Guelin I, Li Z, Chen Y, et al.
bioRxiv
. 2024 Feb;
PMID: 38352498
Cancer development and progression are generally associated with dysregulation of gene expression, often resulting from changes in transcription factor (TF) sequence or expression. Identifying key TFs involved in cancer gene...
5.
Kievits A, Duinkerken B, Fermie J, Lane R, Giepmans B, Hoogenboom J
Ultramicroscopy
. 2023 Nov;
256:113877.
PMID: 37931528
Recent advances in electron microscopy techniques have led to a significant scale up in volumetric imaging of biological tissue. The throughput of electron microscopes, however, remains a limiting factor for...
6.
Berenson A, Lane R, Soto-Ugaldi L, Patel M, Ciausu C, Li Z, et al.
Nat Commun
. 2023 Oct;
14(1):6570.
PMID: 37853017
Cooperativity and antagonism between transcription factors (TFs) can drastically modify their binding to regulatory DNA elements. While mapping these relationships between TFs is important for understanding their context-specific functions, existing...
7.
Kievits A, Lane R, Carroll E, Hoogenboom J
J Microsc
. 2022 Jul;
287(3):114-137.
PMID: 35810393
Detailed knowledge of biological structure has been key in understanding biology at several levels of organisation, from organs to cells and proteins. Volume electron microscopy (volume EM) provides high resolution...
8.
Lane R, Nie J, Kayler L
Transplant Direct
. 2022 Apr;
8(3):e1301.
PMID: 35368988
No abstract available.
9.
Lane R, Wolters A, Giepmans B, Hoogenboom J
Front Mol Biosci
. 2022 Feb;
8:822232.
PMID: 35127826
Volume electron microscopy (EM) of biological systems has grown exponentially in recent years due to innovative large-scale imaging approaches. As a standalone imaging method, however, large-scale EM typically has two...
10.
Kapoor V, Muller S, Keerthivasan S, Brown M, Chalouni C, Storm E, et al.
Nat Immunol
. 2021 Apr;
22(5):571-585.
PMID: 33903764
Fibroblastic reticular cells (FRCs) are specialized stromal cells that define tissue architecture and regulate lymphocyte compartmentalization, homeostasis, and innate and adaptive immunity in secondary lymphoid organs (SLOs). In the present...