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Ryan Keable

Explore the profile of Ryan Keable including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 32
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Recent Articles
1.
Su F, Pfundstein G, Sah S, Zhang S, Keable R, Hagan D, et al.
J Neurochem . 2024 Dec; 169(1):e16279. PMID: 39676071
Neuronal growth regulator 1 (NEGR1) is a synaptic plasma membrane localized cell adhesion molecule implicated in a wide spectrum of psychiatric disorders. By RNAseq analysis of the transcriptomic changes in...
2.
Sah S, Keable R, Pfundstein G, Clemens K, Begg D, Schachner M, et al.
Cereb Cortex . 2023 Jul; 33(18):10047-10065. PMID: 37522285
The neural cell adhesion molecule 2 (NCAM2) regulates axonal organization in the central nervous system via mechanisms that have remained poorly understood. We now show that NCAM2 increases axonal levels...
3.
Keable R, Hu S, Pfundstein G, Kozlova I, Su F, Du X, et al.
Cell Mol Life Sci . 2022 Oct; 79(11):555. PMID: 36251052
Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), also known as β-secretase, is an aspartic protease. The sorting of this enzyme into Rab11-positive recycling endosomes regulates the BACE1-mediated cleavage of...
4.
Kozlova I, Sah S, Keable R, Leshchynska I, Janitz M, Sytnyk V
Front Mol Neurosci . 2020 Dec; 13:592126. PMID: 33281551
Cell adhesion molecules (CAMs) mediate interactions of neurons with the extracellular environment by forming adhesive bonds with CAMs on adjacent membranes or binding to proteins of the extracellular matrix. Binding...
5.
Keable R, Leshchynska I, Sytnyk V
Neuroscientist . 2020 May; 26(5-6):415-437. PMID: 32449484
The efficient targeting of ionotropic receptors to postsynaptic sites is essential for the function of chemical excitatory and inhibitory synapses, constituting the majority of synapses in the brain. A growing...
6.
Bliim N, Leshchynska I, Keable R, Jun Chen B, Curry-Hyde A, Gray L, et al.
Genomics . 2018 Nov; 111(6):1676-1686. PMID: 30465913
Long term potentiation (LTP) is a form of synaptic plasticity. In the present study LTP was induced via activation of synaptic NMDA receptors in primary hippocampal neuron cultures from neonate...