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Ryan E Yoast

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Articles 18
Citations 381
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Recent Articles
1.
Benson J, Romito O, Abdelnaby A, Xin P, Pathak T, Weir S, et al.
J Biol Chem . 2023 Oct; 299(11):105310. PMID: 37778728
T-cell receptor stimulation triggers cytosolic Ca signaling by inositol-1,4,5-trisphosphate (IP)-mediated Ca release from the endoplasmic reticulum (ER) and Ca entry through Ca release-activated Ca (CRAC) channels gated by ER-located stromal-interacting...
2.
Emrich S, Yoast R, Zhang X, Fike A, Wang Y, Bricker K, et al.
Elife . 2023 Feb; 12. PMID: 36803766
The essential role of store-operated Ca entry (SOCE) through Ca release-activated Ca (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE...
3.
Pathak T, Gueguinou M, Walter V, Delierneux C, Johnson M, Zhang X, et al.
Elife . 2023 Feb; 12. PMID: 36757365
No abstract available.
4.
Emrich S, Yoast R, Fike A, Bricker K, Xin P, Zhang X, et al.
Cell Calcium . 2022 Oct; 108:102667. PMID: 36308855
Antigen receptor stimulation triggers cytosolic Ca signals, which activate transcriptional and metabolic programs critical for immune function. B-cell receptor (BCR) engagement causes rapid cytosolic Ca rise through the ubiquitous store-operated...
5.
Johnson M, Benson J, Pathak T, Xin P, McKernan A, Emrich S, et al.
J Biol Chem . 2022 Jul; 298(8):102259. PMID: 35841929
The structural changes of airway smooth muscle (ASM) that characterize airway remodeling (AR) are crucial to the pathogenesis of asthma. During AR, ASM cells dedifferentiate from a quiescent to a...
6.
Johnson M, Xin P, Benson J, Pathak T, Walter V, Emrich S, et al.
Proc Natl Acad Sci U S A . 2021 Dec; 119(1). PMID: 34949717
Airway remodeling and airway hyperresponsiveness are central drivers of asthma severity. Airway remodeling is a structural change involving the dedifferentiation of airway smooth muscle (ASM) cells from a quiescent to...
7.
Emrich S, Yoast R, Trebak M
Annu Rev Physiol . 2021 Oct; 84:355-379. PMID: 34637326
Store-operated Ca entry (SOCE) is a ubiquitous Ca signaling pathway that is evolutionarily conserved across eukaryotes. SOCE is triggered physiologically when the endoplasmic reticulum (ER) Ca stores are emptied through...
8.
Yoast R, Emrich S, Zhang X, Xin P, Arige V, Pathak T, et al.
J Biol Chem . 2021 Sep; 297(4):101174. PMID: 34499925
Mitochondrial Ca uptake tailors the strength of stimulation of plasma membrane phospholipase C-coupled receptors to that of cellular bioenergetics. However, how Ca uptake by the mitochondrial Ca uniporter (MCU) shapes...
9.
Arige V, Emrich S, Yoast R, Trebak M, Yule D
STAR Protoc . 2021 Jul; 2(3):100618. PMID: 34195673
This protocol outlines steps to visualize and detect Ca puffs following photo-liberation of caged inositol-1,4,5-trisphosphate (IP) from HEK-293 cells expressing only the native IPR type 1 receptor using total internal...
10.
Emrich S, Yoast R, Trebak M
Cell Calcium . 2021 Apr; 97:102409. PMID: 33866116
No abstract available.