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Ryan D Baxter

Explore the profile of Ryan D Baxter including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 538
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Recent Articles
1.
Montero M, Rajaram P, Zamora Alvarado J, McCloskey K, Baxter R, Andresen Eguiluz R
Chem Res Toxicol . 2025 Jan; 38(2):231-235. PMID: 39880402
Oxidative byproducts of cannabidiol (CBD) are known to be cytotoxic. However, CBD susceptibility to oxidation and resulting toxicity dissolved in two common solvents, ethanol (EtOH) and dimethyl sulfoxide (DMSO), is...
2.
Baker S, Yaghoubi M, Bidwell S, Pierce S, Hratchian H, Baxter R
J Org Chem . 2022 Jun; 87(13):8492-8502. PMID: 35709498
We report a new method for regioselective aromatic bromination using lactic acid derivatives as halogen bond acceptors with -bromosuccinimide (NBS). Several structural analogues of lactic acid affect the efficiency of...
3.
Galloway J, Sarabia C, Fettinger J, Hratchian H, Baxter R
Org Lett . 2021 Apr; 23(9):3253-3258. PMID: 33844555
Here we report a new chemical reagent for transnitrosation under mild experimental conditions. This new reagent is stable to air and moisture across a broad range of temperatures and is...
4.
Galloway J, Mai D, Baxter R
J Org Chem . 2019 Aug; 84(18):12131-12137. PMID: 31448604
Herein we report the development of radical benzylation reactions of quinones using Selectfluor and catalytic Ag(I) initiators. The reaction is believed to proceed via a C-H abstraction mechanism after Ag(I)-mediated...
5.
Galloway J, Mai D, Baxter R
Org Lett . 2017 Oct; 19(21):5772-5775. PMID: 29043819
A new method for silver-catalyzed Minisci reactions using Selectfluor as a mild oxidant is reported. Heteroarenes and quinones both participate in radical C-H alkylation and arylation from a variety of...
6.
Hua A, Mai D, Martinez R, Baxter R
Org Lett . 2017 May; 19(11):2949-2952. PMID: 28513162
We report a unique example of utilizing unprotected amino acids for benzylic C-H fluorination via a radical process. α-Aminoalkyl radicals are readily generated via oxidative decarboxylation of unprotected amino acids...
7.
Mai D, Baxter R
Org Lett . 2016 Jul; 18(15):3738-41. PMID: 27452036
An efficient and general method for the C-H alkylation of heteroarenes using unprotected amino acids as stable alkyl radical precursors is reported. This one-pot procedure is performed open to air...
8.
Baxter R, Liang Y, Hong X, Brown T, Zare R, Houk K, et al.
ACS Cent Sci . 2015 Dec; 1(8):456-462. PMID: 26640819
Kinetic, spectroscopic, and computational studies of radical C-H arylations highlight the interplay between chemical and physical rate processes in these multiphase reactions. Anomalous concentration dependences observed here may be reconciled...
9.
Jackson E, Malik H, Sormunen G, Baxter R, Liu P, Wang H, et al.
Acc Chem Res . 2015 May; 48(6):1736-45. PMID: 25965694
The control of regiochemistry is a considerable challenge in the development of a wide array of catalytic processes. Simple π-components such as alkenes, alkynes, 1,3-dienes, and allenes are among the...
10.
Haynes 2nd M, Liu P, Baxter R, Nett A, Houk K, Montgomery J
J Am Chem Soc . 2014 Nov; 136(50):17495-504. PMID: 25401337
The mechanism of nickel(0)-catalyzed reductive coupling of aldehydes and alkynes has been studied. Extensive double-labeling crossover studies have been conducted. While previous studies illustrated that phosphine- and N-heterocyclic carbene-derived catalysts...