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Ruth Roman

Explore the profile of Ruth Roman including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 181
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Recent Articles
1.
Bertran-Alamillo J, Gimenez-Capitan A, Roman R, Talbot S, Whiteley R, Floch N, et al.
Mol Cancer . 2023 Jul; 22(1):110. PMID: 37443114
Background: Drugs targeting the spindle assembly checkpoint (SAC), such as inhibitors of Aurora kinase B (AURKB) and dual specific protein kinase TTK, are in different stages of clinical development. However,...
2.
Malapelle U, Pepe F, Pisapia P, Altimari A, Bellevicine C, Brunnstrom H, et al.
J Clin Pathol . 2021 Aug; 76(1):47-52. PMID: 34429353
Aims: Gene fusions assays are key for personalised treatments of advanced human cancers. Their implementation on cytological material requires a preliminary validation that may make use of cell line slides...
3.
Aguado C, Gimenez-Capitan A, Roman R, Rodriguez S, Jordana-Ariza N, Aguilar A, et al.
Diagnostics (Basel) . 2020 Dec; 11(1). PMID: 33374879
The detection of ALK receptor tyrosine kinase (ALK), ROS proto-oncogen1, receptor tyrosine kinase (ROS1), ret proto-oncogen (RET), and MET proto-oncogen exon 14 skipping (Δ) allows for the selection of specific...
4.
Aguado C, Teixido C, Roman R, Reyes R, Gimenez-Capitan A, Marin E, et al.
Mol Oncol . 2020 Nov; 15(2):350-363. PMID: 33236532
MET inhibitors have shown activity in non-small-cell lung cancer patients (NSCLC) with MET amplification and exon 14 skipping (METΔex14). However, patient stratification is imperfect, and thus, response rates have varied...
5.
Bertran-Alamillo J, Cattan V, Schoumacher M, Codony-Servat J, Gimenez-Capitan A, Cantero F, et al.
Nat Commun . 2019 Apr; 10(1):1812. PMID: 31000705
Non-small cell lung cancer (NSCLC) tumors harboring mutations in EGFR ultimately relapse to therapy with EGFR tyrosine kinase inhibitors (EGFR TKIs). Here, we show that resistant cells without the p.T790M...
6.
Verdu M, Trias I, Roman R, Rodon N, Pubill C, Arraiza N, et al.
Appl Immunohistochem Mol Morphol . 2014 Nov; 23(8):565-70. PMID: 25390349
The coexpression of HER2 and EGFR L858R in a solitary nodule removed from the lung, whose mutation was not confirmed by molecular techniques, made us think about the possible existence...
7.
Verdu M, Trias I, Roman R, Rodon N, Garcia-Pelaez B, Calvo M, et al.
Virchows Arch . 2013 May; 462(6):639-44. PMID: 23703293
ERG gene rearrangement has been identified as a highly specific alteration that is present in 40-50 % of prostate carcinomas. The standardization of an immunohistochemical assay with a novel anti-ERG...
8.
Verdu M, Roman R, Calvo M, Rodon N, Garcia B, Gonzalez M, et al.
Mod Pathol . 2011 Feb; 24(5):729-38. PMID: 21336262
Invasive micropapillary carcinoma is associated with frequent lymph node metastasis and adverse clinical outcome. Initially described as a variant of breast and ovarian carcinoma, it has subsequently been found in...
9.
Roman R, Verdu M, Calvo M, Vidal A, Sanjuan X, Jimeno M, et al.
Virchows Arch . 2010 Apr; 456(5):533-41. PMID: 20393748
High microsatellite instability (MSI-H) allows the identification of a subset of colorectal carcinomas associated with good prognosis and a higher incidence of Lynch syndrome. The aim of this work was...
10.
Colomer A, Erill N, Vidal A, Calvo M, Roman R, Verdu M, et al.
Diagn Mol Pathol . 2005 Dec; 14(4):213-23. PMID: 16319691
High-frequency microsatellite instability has been reported to be associated with good prognosis in colorectal adenocarcinoma. However, methods to assess microsatellite instability (MIN) are based on genetic assays and are not...