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Ruth Oefner

Explore the profile of Ruth Oefner including associated specialties, affiliations and a list of published articles. Areas
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Citations 499
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Recent Articles
1.
Linker S, Narvaiza I, Hsu J, Wang M, Qiu F, Mendes A, et al.
Curr Biol . 2022 Oct; 32(22):4797-4807.e5. PMID: 36228612
Unique aspects of human behavior are often attributed to differences in the relative size and organization of the human brain: these structural aspects originate during early development. Recent studies indicate...
2.
Vadodaria K, Mendes A, Mei A, Racha V, Erikson G, Shokhirev M, et al.
Stem Cell Reports . 2021 Mar; 16(4):825-835. PMID: 33667413
Bipolar disorder (BD) is characterized by cyclical mood shifts. Studies indicate that BD patients have a peripheral pro-inflammatory state and alterations in glial populations in the brain. We utilized an...
3.
Marchetto M, Hrvoj-Mihic B, Kerman B, Yu D, Vadodaria K, Linker S, et al.
Elife . 2019 Feb; 8. PMID: 30730291
Comparative analyses of neuronal phenotypes in closely related species can shed light on neuronal changes occurring during evolution. The study of post-mortem brains of nonhuman primates (NHPs) has been limited...
4.
Santos R, Vadodaria K, Jaeger B, Mei A, Lefcochilos-Fogelquist S, Mendes A, et al.
Stem Cell Reports . 2017 Jun; 8(6):1757-1769. PMID: 28591655
Astrocyte dysfunction and neuroinflammation are detrimental features in multiple pathologies of the CNS. Therefore, the development of methods that produce functional human astrocytes represents an advance in the study of...
5.
Muotri A, Marchetto M, Coufal N, Oefner R, Yeo G, Nakashima K, et al.
Nature . 2010 Nov; 468(7322):443-6. PMID: 21085180
Long interspersed nuclear elements-1 (LINE-1 or L1s) are abundant retrotransposons that comprise approximately 20% of mammalian genomes. Active L1 retrotransposons can impact the genome in a variety of ways, creating...