Ruth Boxall
Overview
Explore the profile of Ruth Boxall including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
602
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0
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Recent Articles
1.
Shrine N, Guyatt A, Erzurumluoglu A, Jackson V, Hobbs B, Melbourne C, et al.
Nat Genet
. 2024 Apr;
56(5):1032-1033.
PMID: 38641645
No abstract available.
2.
Holmes M, Kartsonaki C, Boxall R, Lin K, Reeve N, Yu C, et al.
Eur J Prev Cardiol
. 2024 Jan;
31(8):1015-1025.
PMID: 38198221
Aims: Lowering low-density lipoprotein cholesterol (LDL-C) through PCSK9 inhibition represents a new therapeutic approach to preventing and treating cardiovascular disease (CVD). Phenome-wide analyses of PCSK9 genetic variants in large biobanks...
3.
Boxall R, Holmes M, Walters R
Bioinform Adv
. 2023 Sep;
3(1):vbad123.
PMID: 37750069
Summary: We present bubbleHeatmap, an R plotting package which combines elements of a bubble plot and heatmap to conveniently display two numerical variables for each data point across a categorical...
4.
Bovijn J, Krebs K, Chen C, Boxall R, Censin J, Ferreira T, et al.
Sci Transl Med
. 2021 Dec;
13(622):eabf4530.
PMID: 34851696
Triangulation of evidence from clinical trials and human genetics suggests a potential excess risk of cardiovascular disease events arising from therapeutic inhibition of sclerostin.
5.
Bovijn J, Krebs K, Chen C, Boxall R, Censin J, Ferreira T, et al.
Sci Transl Med
. 2020 Jun;
12(549).
PMID: 32581134
Inhibition of sclerostin is a therapeutic approach to lowering fracture risk in patients with osteoporosis. However, data from phase 3 randomized controlled trials (RCTs) of romosozumab, a first-in-class monoclonal antibody...
6.
Shrine N, Guyatt A, Erzurumluoglu A, Jackson V, Hobbs B, Melbourne C, et al.
Nat Genet
. 2019 May;
51(6):1067.
PMID: 31110354
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Shrine N, Guyatt A, Erzurumluoglu A, Jackson V, Hobbs B, Melbourne C, et al.
Nat Genet
. 2019 Feb;
51(3):481-493.
PMID: 30804560
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of European ancestry, we define...
8.
Holmes M, Millwood I, Kartsonaki C, Hill M, Bennett D, Boxall R, et al.
J Am Coll Cardiol
. 2018 Feb;
71(6):620-632.
PMID: 29420958
Background: Blood lipids are established risk factors for myocardial infarction (MI), but uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating metabolites for MI and stroke subtypes. Objectives:...
9.
Millwood I, Bennett D, Holmes M, Boxall R, Guo Y, Bian Z, et al.
JAMA Cardiol
. 2017 Nov;
3(1):34-43.
PMID: 29141072
Importance: Increasing levels of high-density lipoprotein (HDL) cholesterol through pharmacologic inhibition of cholesteryl ester transfer protein (CETP) is a potentially important strategy for prevention and treatment of cardiovascular disease (CVD)....
10.
Walker R, Rybka J, Anderson S, Torrance H, Boxall R, Sussmann J, et al.
J Psychiatr Res
. 2015 Feb;
62:48-55.
PMID: 25708817
Bipolar disorder (BD) is a highly heritable psychiatric disorder characterised by recurrent episodes of mania and depression. Many studies have reported altered gene expression in BD, some of which may...