Russell Pickford
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Explore the profile of Russell Pickford including associated specialties, affiliations and a list of published articles.
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66
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1193
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Recent Articles
1.
Toscan C, McCalmont H, Ashoorzadeh A, Lin X, Fu Z, Doculara L, et al.
Blood Cancer J
. 2024 Nov;
14(1):192.
PMID: 39505850
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that expresses high levels of the enzyme aldo-keto reductase family 1 member C3 (AKR1C3). To exploit this finding, we developed...
2.
Lawson E, Pickford R, Aitken R, Gibb Z, Grupen C, Swegen A
Front Vet Sci
. 2024 Oct;
11:1439550.
PMID: 39430383
The lipidomic secretions of embryos provide a unique opportunity to examine the cellular processes of the early conceptus. In this study we profiled lipids released by the early equine conceptus,...
3.
Biotransformation of 6:2/4:2 fluorotelomer alcohols by Dietzia aurantiaca J3: Enzymes and proteomics
Bhardwaj S, Lee M, OCarroll D, McDonald J, Osborne K, Khan S, et al.
J Hazard Mater
. 2024 Aug;
478:135510.
PMID: 39178776
Per- and polyfluoroalkyl substances (PFAS) are recalcitrant synthetic organohalides known to negatively impact human health. Short-chain fluorotelomer alcohols are considered the precursor of various perfluorocarboxylic acids (PFCAs) in the environment....
4.
Investigations into the role of platelet-activating factor in the peri-conception period of the mare
Lawson E, Ghosh A, Grupen C, Netherton J, Aitken R, Smith N, et al.
Reproduction
. 2024 Jul;
168(4).
PMID: 39056485
In Brief: In many mammals, the lipid platelet-activating factor (PAF) has important functions in female reproduction and fertility. This study shows that PAF is present in the reproductive tissues of...
5.
Galper J, Mori G, McDonald G, Ahmadi Rastegar D, Pickford R, Lewis S, et al.
NPJ Parkinsons Dis
. 2024 Jun;
10(1):123.
PMID: 38918434
Identifying biological factors which contribute to the clinical progression of heterogeneous motor and non-motor phenotypes in Parkinson's disease may help to better understand the disease process. Several lipid-related genetic risk...
6.
Sun J, Yu T, Mirabediny M, Lee M, Jones A, OCarroll D, et al.
Water Res
. 2024 May;
258:121803.
PMID: 38795548
Nano zero-valent metals (nZVMs) have been extensively utilized for decades in the reductive remediation of groundwater contaminated with chlorinated organic compounds, owing to their robust reducing capabilities, simple application, and...
7.
Liew G, Tse B, Ho I, Joachim N, White A, Pickford R, et al.
Invest Ophthalmol Vis Sci
. 2024 May;
61(8):32.
PMID: 38755790
Purpose: Abnormalities in lipid metabolism are implicated in age-related macular degeneration (AMD), but the pathways involved remain unclear. We assessed whether acylcarnitine concentrations, a marker of lipid and mitochondrial metabolism,...
8.
Fu Y, Pickford R, Galper J, Phan K, Wu P, Li H, et al.
NPJ Parkinsons Dis
. 2024 Jan;
10(1):20.
PMID: 38212656
Parkinson's disease (PD) is a chronic neurodegenerative disorder that affects the motor system. Increasing evidence indicates that lysosomal dysfunction is pivotal in the pathogenesis of PD, typically characterized by dysregulation...
9.
Abomughaid M, Tay E, Pickford R, Malladi C, Read S, Coorssen J, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37240132
The hepatitis C virus (HCV) relies on cellular lipid pathways for virus replication and also induces liver steatosis, but the mechanisms involved are not clear. We performed a quantitative lipidomics...
10.
Moles E, Howard C, Huda P, Karsa M, McCalmont H, Kimpton K, et al.
Sci Transl Med
. 2023 May;
15(696):eabm1262.
PMID: 37196067
High-risk childhood leukemia has a poor prognosis because of treatment failure and toxic side effects of therapy. Drug encapsulation into liposomal nanocarriers has shown clinical success at improving biodistribution and...