Ruqiang Liang
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Explore the profile of Ruqiang Liang including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1626
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Recent Articles
1.
Yu J, Kiss Z, Ma W, Liang R, Li T
Cancers (Basel)
. 2025 Jan;
17(1.
PMID: 39796653
Patient-centered precision oncology strives to deliver individualized cancer care. In lung cancer, preclinical models and technological innovations have become critical in advancing this approach. Preclinical models enable deeper insights into...
2.
Lohner H, Han X, Ren J, Liang S, Liang R, Wang H
bioRxiv
. 2024 Dec;
PMID: 39713362
Post-translational modifications (PTMs) are critical regulators of protein function and cellular signaling. While histone deacetylation by histone deacetylases (HDACs) is well established, the role of specific HDACs in modulating non-histone...
3.
Dong C, Gowrishankar R, Jin Y, He X, Gupta A, Wang H, et al.
Nat Neurosci
. 2024 Jul;
27(9):1844-1857.
PMID: 39009835
Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has been limited by a lack of experimental tools that allow for the precise dissection of their complex and diverse...
4.
Han X, Ren J, Lohner H, Yakoumatos L, Liang R, Wang H
J Biol Chem
. 2022 May;
298(6):102036.
PMID: 35588785
Serum- and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that plays important roles in the cellular stress response. While SGK1 has been reported to restrain inflammatory immune responses, the...
5.
Ren J, Han X, Lohner H, Liang R, Liang S, Wang H
J Immunol
. 2021 Jun;
207(1):268-280.
PMID: 34162726
Expression and activity of serum- and glucocorticoid-inducible kinase 1 (SGK1) are associated with many metabolic and inflammatory diseases. In this study, we report that SGK1 promotes alternative macrophage polarization and...
6.
Unger E, Keller J, Altermatt M, Liang R, Matsui A, Dong C, et al.
Cell
. 2020 Dec;
183(7):1986-2002.e26.
PMID: 33333022
Serotonin plays a central role in cognition and is the target of most pharmaceuticals for psychiatric disorders. Existing drugs have limited efficacy; creation of improved versions will require better understanding...
7.
Patriarchi T, Mohebi A, Sun J, Marley A, Liang R, Dong C, et al.
Nat Methods
. 2020 Sep;
17(11):1147-1155.
PMID: 32895537
Genetically encoded dopamine sensors based on green fluorescent protein (GFP) enable high-resolution imaging of dopamine dynamics in behaving animals. However, these GFP-based variants cannot be readily combined with commonly used...
8.
Patriarchi T, Cho J, Merten K, Marley A, Broussard G, Liang R, et al.
Nat Protoc
. 2019 Nov;
14(12):3471-3505.
PMID: 31732722
Multiple aspects of neural activity, from neuronal firing to neuromodulator release and signaling, underlie brain function and ultimately shape animal behavior. The recently developed and constantly growing toolbox of genetically...
9.
Patriarchi T, Cho J, Merten K, Howe M, Marley A, Xiong W, et al.
Science
. 2018 Jun;
360(6396).
PMID: 29853555
Neuromodulatory systems exert profound influences on brain function. Understanding how these systems modify the operating mode of target circuits requires spatiotemporally precise measurement of neuromodulator release. We developed dLight1, an...
10.
Zong L, Zhu Y, Liang R, Zhao H
Sci Rep
. 2016 Jan;
6:19884.
PMID: 26814383
Intercellular genetic communication is an essential requirement for coordination of cell proliferation and differentiation and has an important role in many cellular processes. Gap junction channels possess large pore allowing...