Rukmini Mukherjee
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Explore the profile of Rukmini Mukherjee including associated specialties, affiliations and a list of published articles.
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21
Citations
936
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Recent Articles
1.
Kloet M, Mukhopadhyay R, Mukherjee R, Misra M, Talavera Ormeno C, Tjokrodirijo R, et al.
Bioconjug Chem
. 2025 Feb;
PMID: 39961749
In order to effectively replicate within a host cell, the bacterium secretes effector enzymes into the cytoplasm in order to manipulate cellular host pathways including host ubiquitination. Some of these...
2.
Mukherjee R, Bhattacharya A, Mello-Vieira J, Kuncha S, Hoffmann M, Gonzalez A, et al.
Autophagy
. 2024 Sep;
21(2):407-423.
PMID: 39291751
The KEAP1-NFE2L2 axis is essential for the cellular response against metabolic and oxidative stress. KEAP1 is an adaptor protein of CUL3 (cullin 3) ubiquitin ligase that controls the cellular levels...
3.
Kloet M, Mukhopadhyay R, Mukherjee R, Misra M, Jeong M, Talavera Ormeno C, et al.
J Am Chem Soc
. 2024 Sep;
146(39):26957-26964.
PMID: 39288007
Upon infection of host cells, releases a multitude of effector enzymes into the cell's cytoplasm that hijack a plethora of cellular activities, including the host ubiquitination pathways. Effectors belonging to...
4.
Armstrong L, Lange S, De Cesare V, Matthews S, Nirujogi R, Cole I, et al.
PLoS One
. 2024 Apr;
19(4):e0302418.
PMID: 38626090
[This corrects the article DOI: 10.1371/journal.pone.0253364.].
5.
Bhattacharya A, Mukherjee R, Kuncha S, Brunstein M, Rathore R, Junek S, et al.
Nat Cell Biol
. 2023 Apr;
25(5):685-698.
PMID: 37024685
Acute lysosomal membrane damage reduces the cellular population of functional lysosomes. However, these damaged lysosomes have a remarkable recovery potential independent of lysosomal biogenesis and remain unaffected in cells depleted...
6.
Mukherjee R, Dikic I
Annu Rev Microbiol
. 2022 Sep;
76:211-233.
PMID: 36075095
Ubiquitination is a posttranslational modification that regulates a multitude of cellular functions. Pathogens, such as bacteria and viruses, have evolved sophisticated mechanisms that evade or counteract ubiquitin-dependent host responses, or...
7.
Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection
Liu Y, Mukherjee R, Bonn F, Colby T, Matic I, Glogger M, et al.
Cell Death Differ
. 2021 Jul;
28(10):2957-2969.
PMID: 34285384
SidE family of Legionella effectors catalyze non-canonical phosphoribosyl-linked ubiquitination (PR-ubiquitination) of host proteins during bacterial infection. SdeA localizes predominantly to ER and partially to the Golgi apparatus, and mediates serine...
8.
Armstrong L, Lange S, Dee Cesare V, Matthews S, Nirujogi R, Cole I, et al.
PLoS One
. 2021 Jul;
16(7):e0253364.
PMID: 34270554
Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and plays important roles in the viral life cycle. Being a large, multidomain, transmembrane protein, Nsp3...
9.
Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour A, Shin D, Khan K, et al.
J Biol Chem
. 2021 Jul;
297(2):100925.
PMID: 34214498
Apart from prevention using vaccinations, the management options for COVID-19 remain limited. In retrospective cohort studies, use of famotidine, a specific oral H2 receptor antagonist (antihistamine), has been associated with...
10.
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, et al.
Nature
. 2020 Jul;
587(7835):657-662.
PMID: 32726803
The papain-like protease PLpro is an essential coronavirus enzyme that is required for processing viral polyproteins to generate a functional replicase complex and enable viral spread. PLpro is also implicated...