Rudi G Westendorp
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Explore the profile of Rudi G Westendorp including associated specialties, affiliations and a list of published articles.
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24
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1879
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Recent Articles
1.
van Opstal A, Akintola A, van der Elst M, Westendorp R, Pijl H, van Heemst D, et al.
Sci Rep
. 2017 Oct;
7(1):13327.
PMID: 29042645
The hypothalamus is a crucial structure in the brain that responds to metabolic cues and regulates energy homeostasis. Patients with type 2 diabetes demonstrate a lack of hypothalamic neuronal response...
2.
Akintola A, van Opstal A, Westendorp R, Postmus I, van der Grond J, van Heemst D
Aging (Albany NY)
. 2017 Mar;
9(3):790-802.
PMID: 28291957
Insulin, a vasoactive modulator regulating peripheral and cerebral blood flow, has been consistently linked to aging and longevity. In this proof of principle study, using a randomized, double-blinded, placebo-controlled crossover...
3.
Chaker L, Baumgartner C, den Elzen W, Collet T, Ikram M, Blum M, et al.
J Clin Endocrinol Metab
. 2016 Sep;
101(11):4270-4282.
PMID: 27603906
Context: The currently applied reference ranges for thyroid function are under debate. Despite evidence that thyroid function within the reference range is related with several cardiovascular disorders, its association with...
4.
Akintola A, Noordam R, Jansen S, de Craen A, Ballieux B, Cobbaert C, et al.
PLoS One
. 2015 Oct;
10(10):e0139973.
PMID: 26445499
Background: The validity of continuous glucose monitoring (CGM) is well established in diabetic patients. CGM is also increasingly used for research purposes in normo-glycemic individuals, but the CGM validity in...
5.
Akintola A, Jansen S, van Bodegom D, van der Grond J, Westendorp R, de Craen A, et al.
Front Aging Neurosci
. 2015 Sep;
7:150.
PMID: 26321946
Subclinical hypothyroidism (SCH), defined as elevated thyroid stimulating hormone (TSH) and normal thyroid hormone levels, and cognitive impairment are both common in older people. While the relation between overt hypothyroidism...
6.
Jansen S, Roelfsema F, van der Spoel E, Akintola A, Postmus I, Ballieux B, et al.
J Clin Endocrinol Metab
. 2015 Aug;
100(10):3806-13.
PMID: 26230295
Context: Longevity is associated with changes in circulating levels of thyroid hormone (TH) and/or TSH in animals and humans, but underlying mechanisms remain elusive. Objective: We explored in 38 offspring...
7.
Jansen S, Roelfsema F, Akintola A, Oei N, Cobbaert C, Ballieux B, et al.
PLoS One
. 2015 Jul;
10(7):e0133119.
PMID: 26193655
Objective: The hypothalamic-pituitary-adrenal (HPA)-axis is the most important neuro-endocrine stress response system of our body which is of critical importance for survival. Disturbances in HPA-axis activity have been associated with...
8.
Akintola A, van den Berg A, Altmann-Schneider I, Jansen S, van Buchem M, Slagboom P, et al.
Age (Dordr)
. 2015 Jul;
37(4):9802.
PMID: 26178969
Given the concurrent, escalating epidemic of diabetes mellitus and neurodegenerative diseases, two age-related disorders, we aimed to understand the relation between parameters of glucose metabolism and indices of pathology in...
9.
Akintola A, van den Berg A, van Buchem M, Jansen S, Slagboom E, Westendorp R, et al.
Front Aging Neurosci
. 2015 Jun;
7:92.
PMID: 26074813
Impaired glucose metabolism and type 2 diabetes have been associated with cognitive decline, dementia, and with structural and functional brain features. However, it is unclear whether these associations differ in...
10.
Chaker L, Baumgartner C, den Elzen W, Ikram M, Blum M, Collet T, et al.
J Clin Endocrinol Metab
. 2015 Apr;
100(6):2181-91.
PMID: 25856213
Objective: The objective was to determine the risk of stroke associated with subclinical hypothyroidism. Data Sources And Study Selection: Published prospective cohort studies were identified through a systematic search through...