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Rudi A Dierckx

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Articles 126
Citations 1743
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Recent Articles
21.
Paul S, Khanapur S, Boersma W, Sijbesma J, Ishiwata K, Elsinga P, et al.
Neuroimage . 2014 Feb; 92:83-9. PMID: 24513151
Adenosine A1 receptors (A1Rs) are implied in the modulation of neuroinflammation. Activation of cerebral A1Rs acts as a brake on the microglial response after traumatic brain injury and has neuroprotective...
22.
Noordzij W, Glaudemans A, van Rheenen R, Dierckx R, Slart R, Hazenberg B
Amyloid . 2014 Feb; 21(2):131-3. PMID: 24479618
No abstract available.
23.
Paul S, Khanapur S, Sijbesma J, Ishiwata K, Elsinga P, Meerlo P, et al.
J Nucl Med . 2014 Jan; 55(2):315-20. PMID: 24434292
Unlabelled: Adenosine A1 receptors (A1Rs) in human and rodent brains can be visualized with the radioligand 8-dicyclopropylmethyl-1-(11)C-methyl-3-propylxanthine ((11)C-MPDX) and PET. Here we investigated whether A1R occupancy by nonradioactive agonists and...
24.
Ananias H, Yu Z, Hoving H, Rosati S, Dierckx R, Wang F, et al.
Nucl Med Biol . 2013 Jul; 40(7):933-8. PMID: 23891351
Rationale: The peptide bombesin (BBN) and its derivatives exhibit high binding affinity for the gastrin-releasing peptide receptor (GRPR), which is highly expressed in prostate cancer. We used the BBN-based radiopharmaceutical...
25.
Mirfeizi L, Walsh J, Kolb H, Campbell-Verduyn L, Dierckx R, Feringa B, et al.
Nucl Med Biol . 2013 May; 40(5):710-6. PMID: 23706550
In the last few years click chemistry reactions, and in particular copper-catalyzed cycloadditions have been used extensively for the preparation of new bioconjugated molecules such as (18)F-radiolabeled radiopharmaceuticals for positron...
26.
Juarez-Orozco L, Glauche J, Alexanderson E, Zeebregts C, Boersma H, Glaudemans A, et al.
Eur J Nucl Med Mol Imaging . 2013 Apr; 40(8):1148-54. PMID: 23553081
Purpose: Left ventricular ejection fraction (LVEF) after myocardial infarction is considered to be determined by the size of the infarction and residual function of the spared myocardium. Myocardial perfusion reserve...
27.
Teune L, Renken R, Mudali D, de Jong B, Dierckx R, Roerdink J, et al.
Mov Disord . 2013 Mar; 28(4):547-51. PMID: 23483593
Background: The objective of this study was to validate disease-related metabolic brain patterns for Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Methods: The study included 20 patients with...
28.
Noordzij W, Glaudemans A, Dierckx R, Slart R, Boerboom A, Hazenberg B
Amyloid . 2013 Mar; 20(2):135-7. PMID: 23448125
No abstract available.
29.
Antunes I, Haisma H, Elsinga P, Di Gialleonardo V, van Waarde A, Willemsen A, et al.
Mol Pharm . 2012 Sep; 9(11):3277-85. PMID: 23009590
Extracellular β-glucuronidase (β-GUS) in tumors has been investigated as a target enzyme for prodrug therapy. However, despite encouraging preclinical results, animal studies also indicate that the success of prodrug therapy...
30.
Noordzij W, Glaudemans A, Slart R, Dierckx R, Hazenberg B
Amyloid . 2012 Aug; 19(4):208-11. PMID: 22913327
Histological proof remains the gold standard for the diagnosis of amyloidosis. Nuclear medicine imaging techniques are able to determine the amyloid load in the body. Currently, the best imaging modality...