Ruby Alonso
Overview
Explore the profile of Ruby Alonso including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
322
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Recent Articles
1.
Ruggiu M, Guerin M, Corre B, Bardou M, Alonso R, Russo E, et al.
J Exp Med
. 2024 Feb;
221(4).
PMID: 38417020
Anti-PD-1 therapy targets intratumoral CD8+ T cells to promote clinical responses in cancer patients. Recent evidence suggests an additional activity in the periphery, but the underlying mechanism is unclear. Here,...
2.
Boulch M, Cazaux M, Cuffel A, Guerin M, Garcia Z, Alonso R, et al.
Nat Cancer
. 2023 May;
4(7):968-983.
PMID: 37248395
CD4 T cells and CD4 chimeric antigen receptor (CAR) T cells display highly variable antitumor activity in preclinical models and in patients; however, the mechanisms dictating how and when CD4...
3.
Caudana P, Gonzalo Nunez N, De La Rochere P, Pinto A, Denizeau J, Alonso R, et al.
Cancer Immunol Res
. 2019 Jan;
7(3):443-457.
PMID: 30651291
High-dose IL2 immunotherapy can induce long-lasting cancer regression but is toxic and insufficiently efficacious. Improvements are obtained with IL2/anti-IL2 complexes (IL2Cx), which redirect IL2 action to CD8 T and natural...
4.
Salou M, Legoux F, Gilet J, Darbois A, du Halgouet A, Alonso R, et al.
J Exp Med
. 2018 Dec;
216(1):133-151.
PMID: 30518599
Mucosal-associated invariant T (MAIT) cells are abundant T cells with unique specificity for microbial metabolites. MAIT conservation along evolution indicates important functions, but their low frequency in mice has hampered...
5.
Alonso R, Flament H, Lemoine S, Sedlik C, Bottasso E, Peguillet I, et al.
Nat Commun
. 2018 May;
9(1):2113.
PMID: 29844317
CD4 T cell antitumor responses have mostly been studied in transplanted tumors expressing secreted model antigens (Ags), while most mutated proteins in human cancers are not secreted. The fate of...
6.
Le Dantec C, Alonso R, Fali T, Montero E, Devauchelle V, Saraux A, et al.
Immunol Res
. 2013 Apr;
56(2-3):341-7.
PMID: 23576060
CD6 is a cell surface receptor expressed on the majority of T cells and a subset of B cells. When expressed, CD6 contributes to lymphocyte activation through its extracellular domain...
7.
Hernandez T, Mateo de Acosta C, Lopez-Requena A, Moreno E, Alonso R, Fernandez-Marrero Y, et al.
Mol Immunol
. 2010 Oct;
48(1-3):98-108.
PMID: 20952071
Detailed information on the immunological relevance of α-type anti-idiotypic antibodies is lacking after more than 30 years since Jerne postulated his Idiotypic Network Theory. The B7Y33 mutant is a mouse-human...
8.
Alonso R, Buors C, Le Dantec C, Hillion S, Pers J, Saraux A, et al.
J Autoimmun
. 2010 Sep;
35(4):336-41.
PMID: 20810246
CD6 is one of a pair of related genes encoding CD5-associated receptors on all T cells and a subset of B cells. The current availability of "T1h", a humanized anti-CD6...
9.
Gil L, Lopez C, Lazo L, Valdes I, Marcos E, Alonso R, et al.
Int Immunol
. 2009 Aug;
21(10):1175-83.
PMID: 19692540
Virus-like particles are a highly effective type of subunit vaccine that mimics the overall structure of virus particles without containing infectious genetic material. In this work, a particulate form of...
10.
Alonso R, Huerta V, Leon J, Piedra P, Puchades Y, Guirola O, et al.
Hybridoma (Larchmt)
. 2008 Aug;
27(4):291-301.
PMID: 18707547
Scavenger receptor cysteine-rich (SRCR) domains are evolutionally conserved modules that display complex structures stabilized by key amino acids, while some other residues have evolved with a relative independence, thus allowing...