Ruben Zapata-Perez
Overview
Explore the profile of Ruben Zapata-Perez including associated specialties, affiliations and a list of published articles.
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21
Citations
372
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Recent Articles
1.
Menendez-Coto N, Garcia-Gonzalez C, Baena-Huerta F, Zapata-Perez R, Rabadan-Ros R, Nunez-Delicado E, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684696
Ageing leads to a gradual deterioration of the organs, with the brain being particularly susceptible, often leading to neurodegeneration. This process includes well-known changes such as tau hyperphosphorylation and beta-amyloid...
2.
Marin-Blazquez M, Rovira J, Ramirez-Bajo M, Zapata-Perez R, Rabadan-Ros R
Cell Commun Signal
. 2024 Nov;
22(1):537.
PMID: 39516787
Cardiorenal diseases represent a complex interplay between heart failure and renal dysfunction, being clinically classified as cardiorenal syndromes (CRS). Recently, the contributions of altered nicotinamide adenine dinucleotide (NAD) metabolism, through...
3.
Damschroder D, Zapata-Perez R, Richardson K, Vaz F, Houtkooper R, Wessells R
Dis Model Mech
. 2024 Sep;
17(9).
PMID: 39330214
No abstract available.
4.
Zapata-Perez R, Garcia-Saura A, Scantlebery A, Schomakers B, Rabadan-Ros R, van Weeghel M, et al.
Food Res Int
. 2023 Mar;
165:112560.
PMID: 36869544
Dysregulation of nicotinamide adenine dinucleotide (NAD) homeostasis by increased activity of NAD consumers or reduced NAD biosynthesis plays an important role in the onset of prevalent, often age-related, diseases, such...
5.
Damschroder D, Zapata-Perez R, Richardson K, Vaz F, Houtkooper R, Wessells R
Dis Model Mech
. 2022 Sep;
15(10).
PMID: 36107830
Cardiolipin (CL) is a phospholipid required for proper mitochondrial function. Tafazzin remodels CL to create highly unsaturated fatty acid chains. However, when TAFAZZIN is mutated, CL remodeling is impeded, leading...
6.
van der Stelt I, Shi W, Bekkenkamp-Grovenstein M, Zapata-Perez R, Houtkooper R, de Boer V, et al.
Eur J Nutr
. 2021 Aug;
61(1):329-340.
PMID: 34338868
Purpose: Vitamin B provides nicotinamide adenine dinucleotide (NAD), an essential coenzyme in oxidoreductase reactions. Severe vitamin B deficiency leads to the disease Pellagra, while mild vitamin B deficiency has been...
7.
Zapata-Perez R, Wanders R, van Karnebeek C, Houtkooper R
EMBO Mol Med
. 2021 May;
13(7):e13943.
PMID: 34041853
Depletion of nicotinamide adenine dinucleotide (NAD ), a central redox cofactor and the substrate of key metabolic enzymes, is the causative factor of a number of inherited and acquired diseases...
8.
Canovas-Marquez J, Falk S, Nicolas F, Padmanabhan S, Zapata-Perez R, Sanchez-Ferrer A, et al.
Nucleic Acids Res
. 2021 Apr;
49(9):5294-5307.
PMID: 33877360
Members of the ribonuclease III (RNase III) family regulate gene expression by processing double-stranded RNA (dsRNA). This family includes eukaryotic Dicer and Drosha enzymes that generate small dsRNAs in the...
9.
Zapata-Perez R, Tammaro A, Schomakers B, Scantlebery A, Denis S, Elfrink H, et al.
FASEB J
. 2021 Mar;
35(4):e21456.
PMID: 33724555
Nicotinamide adenine dinucleotide (NAD ) homeostasis is constantly compromised due to degradation by NAD -dependent enzymes. NAD replenishment by supplementation with the NAD precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside...
10.
Zapata-Perez R, Houtkooper R
Nat Metab
. 2020 Jul;
2(3):215-216.
PMID: 32694771
No abstract available.