Ruben C Petreaca
Overview
Explore the profile of Ruben C Petreaca including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
216
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Recent Articles
1.
Al-Marrawi M, Petreaca R, Bouley R
Cancer Genet
. 2025 Jan;
292-293:49-56.
PMID: 39874873
DNA double strand breaks (DSBs) can be generated spontaneously during DNA replication and are repaired primarily by Homologous Recombination (HR). However, efficient repair requires chromatin remodeling to allow the recombination...
2.
Petreaca R, Gasparyan H
Methods Mol Biol
. 2024 Nov;
2862:187-193.
PMID: 39527201
The development of molecular cloning techniques starting in the late 1960s created new tools to facilitate our understanding of gene function. Later advances in PCR and site-specific mutagenesis allowed researchers...
3.
Valentine A, Bosart K, Bush W, Bouley R, Petreaca R
Cancer Genet
. 2024 Nov;
288-289:82-91.
PMID: 39488870
ADAR1 (Adenosine deaminase action on RNA1) is involved in post-transcriptional RNA editing. ADAR1 mutations have been identified in many cancers but its role in tumor formation is still not well...
4.
Bush W, Bosart K, Bouley R, Petreaca R
Mutat Res
. 2024 Jun;
829:111866.
PMID: 38878505
Homologous recombination (HR) is essential for repair of DNA double-strand breaks (DSBs) and restart of stalled or collapsed replication forks. Most cancers are characterized by mutations in components of the...
5.
Bosart K, Petreaca R, Bouley R
MicroPubl Biol
. 2024 Jun;
2024.
PMID: 38828439
SLX4 is an interactor and activator of structure-specific exonuclease that helps resolve tangled recombination intermediates arising at stalled replication forks. It is one of the many factors that assist with...
6.
Raj A, Petreaca R, Mirzaei G
Curr Issues Mol Biol
. 2024 Apr;
46(4):3551-3562.
PMID: 38666952
Genetic biomarkers have played a pivotal role in the classification, prognostication, and guidance of clinical cancer therapies. Large-scale and multi-dimensional analyses of entire cancer genomes, as exemplified by projects like...
7.
Li T, Petreaca R, Forsburg S
PLoS One
. 2024 Apr;
19(4):e0300732.
PMID: 38662722
KAT5 (S. pombe Mst1, human TIP60) is a MYST family histone acetyltransferase conserved from yeast to humans that is involved in multiple cellular activities. This family is characterized in part...
8.
Stan A, Bosart K, Kaur M, Vo M, Escorcia W, Yoder R, et al.
PLoS One
. 2024 Feb;
19(2):e0299114.
PMID: 38408048
Analyzed endometrial cancer (EC) genomes have allowed for the identification of molecular signatures, which enable the classification, and sometimes prognostication, of these cancers. Artificial intelligence algorithms have facilitated the partitioning...
9.
Watson A, Shaffer M, Bouley R, Petreaca R
Cancers (Basel)
. 2023 Sep;
15(18).
PMID: 37760409
Homologous recombination (HR) is the major mechanism of rescue of stalled replication forks or repair of DNA double-strand breaks (DSBs) during S phase or mitosis. In human cells, HR is...
10.
Rasheed S, Bouley R, Yoder R, Petreaca R
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047013
Arginine methylation is a form of posttranslational modification that regulates many cellular functions such as development, DNA damage repair, inflammatory response, splicing, and signal transduction, among others. Protein arginine methyltransferase...