Roxana Rustomjee
Overview
Explore the profile of Roxana Rustomjee including associated specialties, affiliations and a list of published articles.
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43
Citations
2637
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Recent Articles
1.
Ndzamba B, Denti P, McIlleron H, Smith P, Mthiyane T, Rustomjee R, et al.
Antimicrob Agents Chemother
. 2024 Dec;
69(2):e0120024.
PMID: 39714183
Ethambutol is used to treat tuberculosis (TB) in individuals living with HIV. Low concentrations of ethambutol have been reported in patients dosed with the World Health Organization (WHO)-recommended first-line regimen....
2.
Cross R, Longini I, Becker S, Bok K, Boucher D, Carroll M, et al.
PLoS Pathog
. 2022 Oct;
18(10):e1010805.
PMID: 36227853
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine "MARVAC" consortium representing leaders in the field of vaccine research and development aiming...
3.
Finch C, Dowling W, King T, Martinez C, Nguyen B, Roozendaal R, et al.
Vaccines (Basel)
. 2022 Sep;
10(9).
PMID: 36146462
The FDA Animal Rule was devised to facilitate approval of candidate vaccines and therapeutics using animal survival data when human efficacy studies are not practical or ethical. This regulatory pathway...
4.
Finch C, Martinez C, Leffel E, Skiadopoulos M, Hacker A, Mwesigwa B, et al.
Vaccines (Basel)
. 2022 Mar;
10(3).
PMID: 35335000
Clinical vaccine development and regulatory approval generally occurs in a linear, sequential manner: Phase 1: safety, immunogenicity; Phase 2: immunogenicity, safety, dose ranging, and preliminary efficacy; Phase 3: definitive efficacy,...
5.
Mthiyane T, Millard J, Adamson J, Balakrishna Y, Connolly C, Owen A, et al.
Antimicrob Agents Chemother
. 2020 Jan;
64(4).
PMID: 31964788
The distribution of -acetyltransferase 2 gene () polymorphisms varies considerably among different ethnic groups. Information on single-nucleotide polymorphisms in the South African population is limited. We investigated polymorphisms and their...
6.
Mthiyane T, Peter J, Allen J, Connolly C, Davids M, Rustomjee R, et al.
J Thorac Dis
. 2019 Sep;
11(8):3505-3514.
PMID: 31559057
Background: Based on current WHO guidelines, hospitalized tuberculosis (TB) and HIV co-infected patients with CD4 count <100 cells/mm who are urine lipoarabinomannan (LAM) positive should be initiated on TB treatment....
7.
Seddon J, Whittaker E, Kampmann B, Lewinsohn D, Osman M, Hesseling A, et al.
Lancet Infect Dis
. 2019 Jun;
19(9):e322-e329.
PMID: 31221543
Following exposure to tuberculosis and subsequent infection, children often progress to tuberculosis disease more rapidly than adults. And yet the natural history of tuberculosis in children, as a continuum from...
8.
Khan P, Yates T, Osman M, Warren R, van der Heijden Y, Padayatchi N, et al.
Lancet Infect Dis
. 2018 Dec;
19(3):e77-e88.
PMID: 30554996
The emergence and expansion of the multidrug-resistant tuberculosis epidemic is a threat to the global control of tuberculosis. Multidrug-resistant tuberculosis is the result of the selection of resistance-conferring mutations during...
9.
Peters J, Andrews J, Hatherill M, Hermans S, Martinez L, Schurr E, et al.
Lancet Infect Dis
. 2018 Dec;
19(3):e65-e76.
PMID: 30554995
Tuberculosis claims more human lives than any other infectious disease. This alarming epidemic has fuelled the development of novel antimicrobials and diagnostics. However, public health interventions that interrupt transmission have...
10.
Keshavjee S, Amanullah F, Cattamanchi A, Chaisson R, Dobos K, Fox G, et al.
Am J Respir Crit Care Med
. 2018 Oct;
199(5):564-571.
PMID: 30335466
No abstract available.