Roxana Pincheira
Overview
Explore the profile of Roxana Pincheira including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
519
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0
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Recent Articles
1.
Palma M, Riffo E, Farias A, Coliboro-Dannich V, Espinoza-Francine L, Escalona E, et al.
Cell Biosci
. 2023 Dec;
13(1):232.
PMID: 38135881
Background: mTORC2 is a critical regulator of cytoskeleton organization, cell proliferation, and cancer cell survival. Activated mTORC2 induces maximal activation of Akt by phosphorylation of Ser-473, but regulation of Akt...
2.
Riffo E, Palma M, Hepp M, Benitez-Riquelme D, Torres V, Castro A, et al.
Front Cell Dev Biol
. 2022 Nov;
10:1031262.
PMID: 36438565
SALL2/Sall2 is a transcription factor associated with development, neuronal differentiation, and cancer. Interestingly, deficiency leads to failure of the optic fissure closure and neurite outgrowth, suggesting a positive role for...
3.
Armijo M, Escalona E, Pena D, Farias A, Morin V, Baumann M, et al.
Front Pharmacol
. 2022 Jul;
13:912688.
PMID: 35814251
Rheb is a small GTPase member of the Ras superfamily and an activator of mTORC1, a protein complex master regulator of cell metabolism, growth, and proliferation. Rheb/mTORC1 pathway is hyperactivated...
4.
Alvarez C, Quiroz A, Benitez-Riquelme D, Riffo E, Castro A, Pincheira R
Cancers (Basel)
. 2021 Dec;
13(24).
PMID: 34944911
SALL proteins are a family of four conserved C2H2 zinc finger transcription factors that play critical roles in organogenesis during embryonic development. They regulate cell proliferation, survival, migration, and stemness;...
5.
Pincheira R, Zuniga F, Valencia F
Environ Sci Pollut Res Int
. 2021 Jul;
28(46):65573-65594.
PMID: 34319526
Planetary boundaries (PB) is a novel conceptual framework that assesses the state of processes fundamental to the stability of the Earth system. Studies argue a non-linear relationship between economy and...
6.
Farkas C, Quiroz A, Alvarez C, Hermosilla V, Aylwin C, Lomniczi A, et al.
Front Genet
. 2021 Mar;
12:613808.
PMID: 33692826
The SALL2 transcription factor, an evolutionarily conserved gene through vertebrates, is involved in normal development and neuronal differentiation. In disease, SALL2 is associated with eye, kidney, and brain disorders, but...
7.
Escalona E, Munoz M, Pincheira R, Elorza A, Castro A
Front Oncol
. 2020 Aug;
10:1123.
PMID: 32754444
NUAK1 is an AMPK-related kinase located in the cytosol and the nucleus, whose expression associates with tumor malignancy and poor patient prognosis in several cancers. Accordingly, NUAK1 was associated with...
8.
Elizondo-Vega R, Oyarce K, Salgado M, Barahona M, Recabal A, Ordenes P, et al.
Mol Neurobiol
. 2019 Oct;
57(2):896-909.
PMID: 31578706
Feeding behavior regulation is a complex process, which depends on the central integration of different signals, such as glucose, leptin, and ghrelin. Recent studies have shown that glial cells known...
9.
Palma M, Riffo E, Suganuma T, Washburn M, Workman J, Pincheira R, et al.
J Cell Biochem
. 2019 May;
120(9):16088-16107.
PMID: 31090959
NUAK1 is a serine/threonine kinase member of the AMPK-α family. NUAK1 regulates several processes in tumorigenesis; however, its regulation and molecular targets are still poorly understood. Bioinformatics analysis predicted that...
10.
Fuentes-Villalobos F, Farkas C, Riquelme-Barrios S, Armijo M, Soto-Rifo R, Pincheira R, et al.
Biochim Biophys Acta Gene Regul Mech
. 2019 May;
1862(6):657-669.
PMID: 31075539
Variation in Disrupted-in-Schizophrenia 1 (DISC1) increases the risk for neurodegenerative diseases, schizophrenia, and other mental disorders. However, the functions of DISC1 associated with the development of these diseases remain unclear....