Rowan Higgs
Overview
Explore the profile of Rowan Higgs including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
32
Citations
986
Followers
0
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Recent Articles
1.
Wynne C, Lazzari E, Smith S, McCarthy E, Gabhann J, Kallal L, et al.
PLoS One
. 2014 Jul;
9(7):e101503.
PMID: 24999993
In recent years members of the tripartite motif-containing (TRIM) family of E3 ubiquitin ligases have been shown to both positively and negatively regulate viral defence and as such are emerging...
2.
Mielke L, Jones S, Raverdeau M, Higgs R, Stefanska A, Groom J, et al.
J Exp Med
. 2013 May;
210(6):1117-24.
PMID: 23690441
Retinoic acid (RA), a vitamin A metabolite, modulates mucosal T helper cell responses. Here we examined the role of RA in regulating IL-22 production by γδ T cells and innate...
3.
Marshall N, Galvin K, Corcoran A, Boon L, Higgs R, Mills K
Cancer Res
. 2011 Dec;
72(3):581-91.
PMID: 22158905
The immunosuppressive microenvironment in tumors hampers the induction of antitumor immunity by vaccines or immunotherapies. Toll-like receptor (TLR) ligands have the potential to treat tumors, but they can exert a...
4.
Smith S, Gabhann J, Higgs R, Stacey K, Wahren-Herlenius M, Espinosa A, et al.
Arthritis Rheum
. 2011 Dec;
64(5):1601-9.
PMID: 22127978
Objective: To examine the role of interferon regulatory factor 3 (IRF-3) in the regulation of interleukin-23 (IL-23) production in patients with systemic lupus erythematosus (SLE). Methods: Bone marrow-derived macrophages were...
5.
Jefferies C, Wynne C, Higgs R
Nat Rev Immunol
. 2011 Aug;
11(9):617-25.
PMID: 21866173
The concept that viral sensing systems, via their ability to drive pro-inflammatory cytokine and interferon production, contribute to the development of autoimmune and autoinflammatory disease is supported by a wide...
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