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Ross A Davey

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Citations 74
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Recent Articles
1.
McCann L, Haywood M, Ren B, Simpson A, Guilhaus M, Wasinger V, et al.
J Proteome Res . 2007 Jul; 6(8):3108-13. PMID: 17602683
We have developed a methodology to selectively isolate and identify proteins associated with the luminal surface of blood vessels using in vivo biotinylation, streptavidin-affinity chromatography, and SDS-PAGE/LC-MS/MS. This had sufficient...
2.
Murphy S, Davey R, Gu X, Haywood M, McCann L, Mather L, et al.
J Neurooncol . 2007 May; 85(2):181-9. PMID: 17534579
With the aim of improving the treatment of glioblastoma multiforme, we investigated the potential of thalidomide to enhance the effectiveness of cisplatin chemotherapy in a rat glioma model. Female F344...
3.
Murphy S, Boyle F, Davey R, Gu X, Mather L
J Pharm Pharmacol . 2007 Jan; 59(1):105-14. PMID: 17227627
Thalidomide is currently under evaluation as an anti-angiogenic agent in cancer treatment, alone and in combination with cytotoxic agents. Thalidomide is a racemate with known pharmacologic and pharmacokinetic enantioselectivity. In...
4.
Stordal B, Davey M, Davey R
Cancer Chemother Pharmacol . 2005 Nov; 58(2):256-65. PMID: 16283310
Cisplatin produces good responses in solid tumours including small cell lung cancer (SCLC) but this is limited by the development of resistance. Oxaliplatin is reported to show activity against some...
5.
Jackson C, Xue M, Thompson P, Davey R, Whitmont K, Smith S, et al.
Wound Repair Regen . 2005 Jun; 13(3):284-94. PMID: 15953048
Activated protein C (APC) is a serine protease that plays a central role in physiological anticoagulation, and has more recently been shown to be a potent anti-inflammatory mediator. Using cultured...
6.
Henness S, Davey M, Harvie R, Banyer J, Wasinger V, Corthals G, et al.
Radiat Res . 2004 May; 161(5):495-503. PMID: 15161375
Small cell lung cancer (SCLC) initially responds well to chemotherapy and fractionated radiotherapy, but resistance to these treatments eventually develops in the vast majority of cases. To understand how resistance...
7.
Davey R, Locke V, Henness S, Harvie R, Davey M
Anticancer Res . 2004 May; 24(2A):465-71. PMID: 15152945
Background: The H69-EPR, H69-CP, H69-VP and H69/R38 resistant sublines of the classic small cell lung cancer (SCLC) line have proven useful in studies of resistance and its circumvention with paclitaxel....
8.
Locke V, Davey R, Davey M
Anticancer Drugs . 2003 Sep; 14(7):523-31. PMID: 12960736
Small cell lung cancer (SCLC) responds to treatment with cisplatin and etoposide, but relapse is rapid and survival rates are low. Our aims were to determine the mechanisms of resistance...
9.
Davey R, Davey M, Cullen K, Wells X, Francis C, Yang Q, et al.
Br J Pharmacol . 2002 Dec; 137(8):1280-6. PMID: 12466237
1. Increasing the lipophilicity is a strategy often used to improve a compound's cellular uptake and retention but this may also convert it into a substrate for an ATP-dependent transporter...
10.
Henness S, Davey M, Harvie R, Davey R
Int J Radiat Oncol Biol Phys . 2002 Oct; 54(3):895-902. PMID: 12377343
Purpose: After standard treatment with chemotherapy and radiotherapy, small-cell lung cancer (SCLC) often develops resistance to both treatments. Our aims were to establish if fractionated radiation treatment alone would induce...