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Rosebud O Roberts

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Articles 176
Citations 10191
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Recent Articles
1.
Vassilaki M, Aakre J, Kremers W, Lesnick T, Mielke M, Geda Y, et al.
Ann Clin Transl Neurol . 2020 Apr; 7(4):474-485. PMID: 32314554
Objective: To examine the association of baseline elevated brain amyloid and neurodegeneration with changes in activities of daily living in participants without dementia (ND; i.e., cognitively unimpaired and participants with...
2.
Vassilaki M, Syrjanen J, Kremers W, Hagen P, Knopman D, Mielke M, et al.
J Am Geriatr Soc . 2020 Feb; 68(6):1250-1255. PMID: 32086949
Objective: To examine the association between being a medical doctor (MD) and the risk of incident dementia. Design: Cohort study. Setting: Olmsted County, Minnesota. Participants: A total of 3460 participants...
3.
Vassilaki M, Aakre J, Knopman D, Kremers W, Mielke M, Geda Y, et al.
Age Ageing . 2019 Aug; 48(6):888-894. PMID: 31437275
Background: hearing loss has been associated with mild cognitive impairment (MCI) and dementia. Studies have not assessed whether hearing difficulties (HD) that interfere with daily activities as reported by partners...
4.
Jack Jr C, Therneau T, Weigand S, Wiste H, Knopman D, Vemuri P, et al.
JAMA Neurol . 2019 Jul; 76(10):1174-1183. PMID: 31305929
Importance: A National Institute on Aging-Alzheimer's Association (NIA-AA) workgroup recently published a research framework in which Alzheimer disease is defined by neuropathologic or biomarker evidence of β-amyloid plaques and tau...
5.
Jack Jr C, Wiste H, Therneau T, Weigand S, Knopman D, Mielke M, et al.
JAMA . 2019 Jun; 321(23):2316-2325. PMID: 31211344
Importance: A National Institute on Aging and Alzheimer's Association workgroup proposed a research framework for Alzheimer disease in which biomarker classification of research participants is labeled AT(N) for amyloid, tau,...
6.
Lowe V, Bruinsma T, Wiste H, Min H, Weigand S, Fang P, et al.
Neurology . 2019 Jun; 93(1):e29-e39. PMID: 31147421
Objective: To assess cross-sectional associations of neurofibrillary tangles, measured by tau-PET, with cognitive performance in cognitively unimpaired (CU) adults. Methods: Tau- and amyloid-PET were performed in 579 CU participants aged...
7.
Krell-Roesch J, Vassilaki M, Mielke M, Kremers W, Lowe V, Vemuri P, et al.
Transl Psychiatry . 2019 Mar; 9(1):123. PMID: 30923322
Neuropsychiatric symptoms (NPS) are a risk factor for cognitive impairment and are associated with cortical β-amyloid (Aβ) deposition. We conducted a cross-sectional study derived from the ongoing population-based Mayo Clinic...
8.
Cerhan J, Butts A, Syrjanen J, Aakre J, Brown P, Petersen R, et al.
Mayo Clin Proc . 2019 Feb; 94(2):254-261. PMID: 30711123
Objective: To determine the frequency of incidental meningioma and identify associated factors in a population-based sample of participants who systematically underwent brain imaging. Patients And Methods: We searched the Mayo...
9.
Graff-Radford J, Botha H, Rabinstein A, Gunter J, Przybelski S, Lesnick T, et al.
Neurology . 2018 Dec; 92(3):e253-e262. PMID: 30568001
Objective: To describe the prevalence of cerebral microbleeds (CMBs) and determine the association between CMBs and β-amyloid burden on PET. Methods: From the population-based Mayo Clinic Study of Aging, 1,215...
10.
Petersen R, Lundt E, Therneau T, Weigand S, Knopman D, Mielke M, et al.
Ann Neurol . 2018 Dec; 85(1):155-160. PMID: 30521086
Despite much attention to the use of biomarkers for predicting Alzheimer disease, little information is available at the individual level. We used the population-based Mayo Clinic Study of Aging to...