Roque P Almeida
Overview
Explore the profile of Roque P Almeida including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
996
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0
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Recent Articles
1.
Santos E, Daltro R, Regis-Silva C, Pavan T, de Oliveira F, da Silva A, et al.
Diagnostics (Basel)
. 2023 Nov;
13(22).
PMID: 37998606
This study focuses on developing accurate immunoassays for diagnosing Chagas disease (CD), a challenging task due to antigenic similarities between and other parasites, leading to cross-reactivity. To address this challenge,...
2.
Ng W, Liu X, Ling Z, Santos C, Magalhaes L, Kueh A, et al.
Nat Commun
. 2023 Oct;
14(1):6605.
PMID: 37884534
Arthritogenic alphaviruses are positive-strand RNA viruses that cause debilitating musculoskeletal diseases affecting millions worldwide. A recent discovery identified the four-and-a-half-LIM domain protein 1 splice variant A (FHL1A) as a crucial...
3.
Liu X, Poo Y, Alves J, Almeida R, Mostafavi H, Tang P, et al.
mBio
. 2022 Mar;
13(2):e0028922.
PMID: 35254128
Alphaviral arthritides caused by mosquito-borne arboviruses such as chikungunya virus (CHIKV) can persist for months after the initial acute disease. Here, we investigated the contribution of interleukin-17 (IL-17), a cytokine...
4.
Maruyama S, de Santana A, Takamiya N, Takahashi T, Rogerio L, Oliveira C, et al.
Emerg Infect Dis
. 2019 Oct;
25(11):2088-2092.
PMID: 31625841
Through whole-genome sequencing analysis, we identified non-Leishmania parasites isolated from a man with a fatal visceral leishmaniasis-like illness in Brazil. The parasites infected mice and reproduced the patient's clinical manifestations....
5.
Barrios M, Campos V, Peres N, de Oliveira L, Cazzaniga R, Santos M, et al.
Front Cell Infect Microbiol
. 2019 Sep;
9:311.
PMID: 31544067
Isolated growth hormone (GH) deficiency (IGHD) affects approximately 1 in 4,000 to 1 in 10,000 individuals worldwide. We have previously described a large cohort of subjects with IGHD due to...
6.
Gupta G, Santana A, Gomes C, Turatti A, Milanezi C, Bueno Filho R, et al.
Cell Immunol
. 2019 May;
341:103920.
PMID: 31078283
Localized cutaneous leishmaniasis (LCL) can ultimately progress to chronic ulcerated lesions with strong local inflammatory reactions. The functional role of certain inflammasomes in mediating inflammation caused by Leishmania braziliensis needs...
7.
Barbosa L, Fiuza P, Borges L, Rolim F, Andrade M, Luz N, et al.
Front Immunol
. 2018 Aug;
9:1818.
PMID: 30154785
Necroptosis is a pro-inflammatory cell death, which happens in the context of caspase-8 inhibition, allowing activation of the receptor interacting protein kinase 1-receptor interacting protein kinase 3-mixed lineage kinase domain-like...
8.
Quintela-Carvalho G, Luz N, Celes F, Zanette D, Andrade D, Menezes D, et al.
Front Immunol
. 2017 Dec;
8:1620.
PMID: 29218050
Free heme is an inflammatory molecule capable of inducing migration and activation of neutrophils. Here, we examine the heme-driven oxidative stress-associated cell death mechanisms in human neutrophils infected with ,...
9.
Bomfim L, Magalhaes L, Santos-Filho M, Peres N, Correa C, Tanajura D, et al.
Front Microbiol
. 2017 Dec;
8:2265.
PMID: 29201022
Visceral leishmaniasis (VL) is a systemic transmissible disease that remains to be a major global health problem. The inflammatory response during VL is characterized by the release of several cytokines...
10.
Bosch I, de Puig H, Hiley M, Carre-Camps M, Perdomo-Celis F, Narvaez C, et al.
Sci Transl Med
. 2017 Sep;
9(409).
PMID: 28954927
The recent Zika virus (ZIKV) outbreak demonstrates that cost-effective clinical diagnostics are urgently needed to detect and distinguish viral infections to improve patient care. Unlike dengue virus (DENV), ZIKV infections...