Rongtuan Lin
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Explore the profile of Rongtuan Lin including associated specialties, affiliations and a list of published articles.
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107
Citations
5986
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Recent Articles
11.
Totten S, Im Y, Cepeda Canedo E, Najyb O, Nguyen A, Hebert S, et al.
Nat Commun
. 2021 Jun;
12(1):3299.
PMID: 34083537
Bioenergetic perturbations driving neoplastic growth increase the production of reactive oxygen species (ROS), requiring a compensatory increase in ROS scavengers to limit oxidative stress. Intervention strategies that simultaneously induce energetic...
12.
Zhao J, Guo S, Yi D, Li Q, Ma L, Zhang Y, et al.
Antiviral Res
. 2021 Apr;
190:105078.
PMID: 33894278
Antiviral therapeutics is one effective avenue to control and end this devastating COVID-19 pandemic. The viral RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 has been recognized as a valuable target of...
13.
Zhang X, Chapat C, Wang P, Choi J, Li Q, Luo J, et al.
Mol Cell
. 2021 Feb;
81(6):1187-1199.e5.
PMID: 33581076
Type I interferons (IFNs) are critical cytokines in the host defense against invading pathogens. Sustained production of IFNs, however, is detrimental to the host, as it provokes autoimmune diseases. Thus,...
14.
Huang B, Huang S, Chen X, Liu X, Wu Q, Wang Y, et al.
Front Cell Infect Microbiol
. 2019 Sep;
9:322.
PMID: 31552201
Malaria, a mosquito-borne infectious disease, is a severe health problem worldwide. As reported, some anti-malarial drugs with anti-parasitic properties also block mast cells (MCs) activities. It is hypothesized that MCs...
15.
Cao L, Liu S, Li Y, Yang G, Luo Y, Li S, et al.
Cell Host Microbe
. 2019 Sep;
26(3):369-384.e8.
PMID: 31513772
Pathogen pattern recognition receptors (PRRs) trigger innate immune responses to invading pathogens. All known PRRs for viral RNA have extranuclear localization. However, for many viruses, replication generates dsRNA in the...
16.
Chang N, Lin R, Sze C, Aqeilan R
Front Oncol
. 2019 Aug;
9:719.
PMID: 31428585
No abstract available.
17.
Acchioni C, Remoli A, Marsili G, Acchioni M, Nardolillo I, Orsatti R, et al.
J Virol
. 2019 Jun;
93(18).
PMID: 31243131
Current combination antiretroviral therapies (cART) are unable to eradicate HIV-1 from infected individuals because of the establishment of proviral latency in long-lived cellular reservoirs. The shock-and-kill approach aims to reactivate...
18.
Olagnier D, Brandtoft A, Gunderstofte C, Villadsen N, Krapp C, Thielke A, et al.
Nat Commun
. 2018 Aug;
9(1):3506.
PMID: 30158636
The transcription factor Nrf2 is a critical regulator of inflammatory responses. If and how Nrf2 also affects cytosolic nucleic acid sensing is currently unknown. Here we identify Nrf2 as an...
19.
Hansen A, Buchan G, Ruhl M, Mukai K, Salvatore S, Ogawa E, et al.
Proc Natl Acad Sci U S A
. 2018 Aug;
115(33):E7768-E7775.
PMID: 30061387
The adaptor molecule stimulator of IFN genes (STING) is central to production of type I IFNs in response to infection with DNA viruses and to presence of host DNA in...
20.
Yang L, Wang L, Ketkar H, Ma J, Yang G, Cui S, et al.
Nat Commun
. 2018 Jun;
9(1):2329.
PMID: 29899553
The ubiquitin regulatory X domain-containing proteins (UBXNs) are likely involved in diverse biological processes. Their physiological functions, however, remain largely unknown. Here we present physiological evidence that UBXN3B positively regulates...