Rongqi Duan
Overview
Explore the profile of Rongqi Duan including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
182
Followers
0
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Recent Articles
1.
Zhou P, Watt J, Mai J, Cao H, Li Z, Chen Z, et al.
Front Immunol
. 2024 Sep;
15:1430928.
PMID: 39281669
The outbreak of coronavirus disease 19 (COVID-19) has highlighted the demand for vaccines that are safe and effective in inducing systemic and airway mucosal immunity against the aerosol transmission of...
2.
Cao H, Mai J, Zhou Z, Li Z, Duan R, Watt J, et al.
Cell Biosci
. 2021 Dec;
11(1):202.
PMID: 34879865
Background: The ongoing COVID-19 pandemic has resulted in 185 million recorded cases and over 4 million deaths worldwide. Several COVID-19 vaccines have been approved for emergency use in humans and...
3.
Cao H, Duan R, Hu J
Genes (Basel)
. 2020 May;
11(5).
PMID: 32443586
Cystic Fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator () gene, and CF patients require life-long treatment. Although modulators show a great potential for treating...
4.
Xia E, Zhang Y, Cao H, Li J, Duan R, Hu J
Genes (Basel)
. 2019 Jan;
10(1).
PMID: 30641980
Cystic fibrosis (CF) is an inherited monogenic disorder, amenable to gene-based therapies. Because CF lung disease is currently the major cause of mortality and morbidity, and the lung airway is...
5.
Xia E, Duan R, Shi F, Seigel K, Grasemann H, Hu J
Mol Ther Nucleic Acids
. 2018 Dec;
13:699-709.
PMID: 30513454
The CRISPR-Cas9 system is attractive for gene therapy, as it allows for permanent genetic correction. However, as a new technology, Cas9 gene editing in clinical applications faces major challenges, such...
6.
Cao H, Ouyang H, Grasemann H, Bartlett C, Du K, Duan R, et al.
Hum Gene Ther
. 2018 Jan;
29(6):643-652.
PMID: 29320887
A major challenge in developing gene-based therapies for airway diseases such as cystic fibrosis (CF) is sustaining therapeutic levels of transgene expression over time. This is largely due to airway...
7.
Lam S, Cao H, Wu J, Duan R, Hu J
Genes Dis
. 2015 Jul;
1(2):227-237.
PMID: 26161435
There have been significant advancements in the field of retinal gene therapy in the past several years. In particular, therapeutic efficacy has been achieved in three separate human clinical trials...
8.
Guan R, Wen X, Wu J, Duan R, Cao H, Lam S, et al.
Mol Cell Biochem
. 2012 Feb;
365(1-2):211-22.
PMID: 22350815
ZNF403, also known as GGNBP2 (gametogenetin binding protein 2), is a highly conserved gene implicated in spermatogenesis. However, the exact biological function of ZNF403 is not clear. In this study,...
9.
Kushwah R, Oliver J, Duan R, Zhang L, Keshavjee S, Hu J
J Virol
. 2012 Jan;
86(7):3422-35.
PMID: 22258241
The success of helper-dependent adenoviral (HD-Ad) vector-mediated lung gene therapy is hampered by the host immune response, which limits pulmonary transgene expression following multiple rounds of vector readminstration. Here, we...
10.
Wu L, Lam S, Cao H, Guan R, Duan R, van der Kooy D, et al.
Cell Biosci
. 2011 Jun;
1(1):15.
PMID: 21711866
This study describes the successful delivery of helper-dependent adenoviral vectors to the mouse retina with long term and robust levels of reporter expression in the retina without apparent adverse effects....